Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 6/20 | 0.32 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3575203 | 0.80 | CASR (0.35) | CCR5 | |
| SCHEMBL3573543 | 0.80 | AOC3 (0.33) | AOC3CCR5TOP2ATOP2B | |
| SCHEMBL3573546 | 0.80 | CASR (0.39) | — | |
| SCHEMBL1096395 | 0.77 | ESR1 (0.34) | CCR5ESR1ESR2 | |
| SCHEMBL1096396 | 0.77 | ESR1 (0.33) | CCR5ESR1ESR2 | |
| SCHEMBL1096155 | 0.76 | AOC3 (0.31) | AOC3CCR5TOP2ATOP2B | |
| SCHEMBL3572894 | 0.75 | CASR (0.35) | ESR1ESR2 | |
| SCHEMBL1094613 | 0.73 | ESR1 (0.34) | CCR5ESR1ESR2 | |
| SCHEMBL1094614 | 0.72 | ESR1 (0.33) | CCR5ESR1ESR2 | |
| SCHEMBL4758707 | 0.71 | CCR5 (0.39) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029687-A1 | PIPERIDINE DERIVATIVE OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029687-A1 | PIPERIDINE DERIVATIVE OR SALT THEREOF | CASR, CYP2R1, HCAR1 | AOC3 2730/4885CCR5 542/4885TOP2A 4655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.