Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 4/20 | 0.49 |
| ▸ | AURKA | O14965 | 2/20 | 0.49 |
| ▸ | CHEK2 | O96017 | 7/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 5/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | CLK2 | P49760 | 1/20 | 0.38 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3587289 | 0.86 | AURKA (0.56) | AURKBAURKACHEK2PARP1PARP2 | |
| SCHEMBL3574580 | 0.84 | AURKA (0.66) | AURKBAURKACHEK2PARP1PLA2G2A | |
| SCHEMBL3576337 | 0.83 | PARP1 (0.49) | AURKBAURKACHEK2PARP1 | |
| SCHEMBL3576982 | 0.83 | AURKA (0.52) | AURKBAURKACHEK2ACHEPARP1 | |
| SCHEMBL3582282 | 0.83 | AURKB (0.61) | AURKBAURKACHEK2ACHEPARP1 | |
| SCHEMBL3580358 | 0.82 | PARP1 (0.53) | AURKBAURKACHEK2PARP1PARP2 | |
| SCHEMBL3577227 | 0.82 | AURKA (0.53) | AURKBAURKACHEK2PARP1PARP2 | |
| SCHEMBL3574441 | 0.80 | AURKA (0.75) | AURKBAURKACHEK2ACHEPARP1 | |
| SCHEMBL3582849 | 0.80 | AURKB (0.58) | AURKBAURKACHEK2ACHEPARP1 | |
| SCHEMBL3579920 | 0.80 | AURKA (0.49) | AURKBAURKACHEK2ACHEPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781596-B1 | Substituted 2-phenylbenzimidazoles, the production thereof and their use | ABBOTT LABORATORIES (US) | 2010-08-24 | — | — | US | disclosed |