Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3576804 | 0.98 | SIGMAR1 (0.36) | MCHR1SIGMAR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3578672 | 0.92 | GBA1 (0.34) | SIGMAR1ALDH1A1MAPTSMN1; SMN2OPRK1 | |
| SCHEMBL3577036 | 0.91 | MCHR1 (0.43) | MCHR1SIGMAR1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL3583638 | 0.88 | C5AR1 (0.41) | MCHR1MAPTOPRM1OPRD1C5AR1 | |
| SCHEMBL3574398 | 0.86 | STAT3 (0.37) | SMN1; SMN2CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL3573512 | 0.85 | HDAC1 (0.36) | SIGMAR1CYP3A4TSHROPRM1OPRD1 | |
| SCHEMBL3584245 | 0.84 | SIGMAR1 (0.34) | SIGMAR1ALDH1A1MAPTSMN1; SMN2OPRK1 | |
| SCHEMBL3576692 | 0.84 | ESRRG (0.37) | SIGMAR1OPRM1OPRD1C5AR1 | |
| SCHEMBL3572810 | 0.83 | OPRM1 (0.34) | SIGMAR1ALDH1A1MAPTSMN1; SMN2OPRK1 | |
| SCHEMBL3573226 | 0.83 | CNR1 (0.37) | SMN1; SMN2CYP1A2CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |