Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 3/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 5/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3576351 | 0.92 | MCHR1 (0.35) | SIGMAR1ALDH1A1OPRM1OPRD1MAPT | |
| SCHEMBL3576804 | 0.90 | SIGMAR1 (0.36) | SIGMAR1ALDH1A1OPRM1OPRD1MAPT | |
| SCHEMBL3584126 | 0.84 | ESRRG (0.36) | GBA1SIGMAR1SSTR2SSTR4OPRM1 | |
| SCHEMBL3584245 | 0.83 | SIGMAR1 (0.34) | SIGMAR1ALDH1A1OPRM1OPRD1MAPT | |
| SCHEMBL3584062 | 0.82 | GBA1 (0.34) | GBA1SIGMAR1SSTR2SSTR4OPRM1 | |
| SCHEMBL3577036 | 0.82 | MCHR1 (0.43) | SIGMAR1ALDH1A1OPRM1OPRD1MAPT | |
| SCHEMBL3572810 | 0.82 | OPRM1 (0.34) | SIGMAR1ALDH1A1OPRM1OPRD1MAPT | |
| SCHEMBL3583638 | 0.80 | C5AR1 (0.41) | OPRM1OPRD1MAPT | |
| SCHEMBL3574398 | 0.79 | STAT3 (0.37) | SMN1; SMN2CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL3575573 | 0.76 | HSP90AA1 (0.36) | GBA1SSTR2SSTR4OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |