Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4964734 | 0.88 | TDP1 (0.43) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL3577130 | 0.81 | PRKCA (0.50) | TDP1TSHRCHRM1CHRM2CHRM4 | |
| SCHEMBL20599618 | 0.81 | — | — | |
| SCHEMBL20599585 | 0.81 | — | — | |
| SCHEMBL11488939 | 0.81 | — | — | |
| SCHEMBL2100144 | 0.81 | — | — | |
| SCHEMBL8719451 | 0.77 | TSHR (0.40) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL11461584 | 0.77 | ALOX15 (0.43) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL6966711 | 0.77 | TDP1 (0.46) | TDP1TSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL8723281 | 0.75 | TDP1 (0.75) | TDP1TSHRALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106316878-B | A kind of preparation method of iomeprol impurity | 重庆常捷医药有限公司 | 2018-01-19 | — | — | CN | claimed |
| CN-104666246-A | Orally Bioavailable Lipid-based Constructs | SDG INC AN OHIO CORPRATION | 2015-06-03 | — | — | CN | claimed |
| CN-102015624-B | Preparation method of iopromide | LG LIFE SCIENCES LTD | 2013-11-06 | — | — | CN | claimed |
| CN-102015624-A | New preparation method of iopromide | LG LIFE SCIENCES LTD | 2011-04-13 | — | — | CN | claimed |
| CN-101917971-A | Orally bioavailable lipid-based structures | SDG INC AN OHIO CORP | 2010-12-15 | — | — | CN | claimed |
| US-6803485-B2 | WATER SOLUBLE CONTRAST AGENT | BRACCO IMAGING S.P.A. (IT) | 2004-10-12 | — | — | US | claimed |
| EP-1154986-B1 | PROCESS FOR THE PREPARATION OF IOPAMIDOL | BRACCO IMAGING SPA (IT) | 2004-06-09 | — | — | EP | claimed |
| US-20010056206-A1 | PROCESS FOR THE PREPARATION OF IOPAMIDOL | BRACCO IMAGING S.P.A. (IT) | 2001-12-27 | — | — | US | claimed |
| EP-1154986-A1 | PROCESS FOR THE PREPARATION OF IOPAMIDOL | ABBOTT LABORATORIES (US) | 2001-11-21 | — | — | EP | claimed |
| WO-2000050385-A1 | PROCESS FOR THE PREPARATION OF IOPAMIDOL | ABBOTT LABORATORIES (US) | 2000-08-31 | — | — | WO | claimed |
| EP-0088940-B1 | PYRIDINE-CARBOXYLIC-ACID ESTERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS | BAYER AG (DE) | 1986-05-21 | — | — | EP | claimed |
| EP-0034894-B1 | 2-(1-PIPERAZINYL)-2,4,6-CYCLOHEPTATRIEN-1-ONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, INTERMEDIATES USED IN THE PROCESSES AND THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE DERIVATIVES | AYERST, MCKENNA AND HARRISON INC. (CA) | 1984-09-12 | — | — | EP | claimed |
| US-4469694-A | 2-(1-Piperazinyl)-2,4,6-cycloheptatrien-1-one derivatives | AYERST, MCKENNA & HARRISON INC. (CA) | 1984-09-04 | — | — | US | claimed |
| EP-0034894-A2 | 2-(1-Piperazinyl)-2,4,6-cycloheptatrien-1-one derivatives, processes for their preparation, intermediates used in the processes and the preparation thereof and pharmaceutical compositions containing the derivatives | AYERST, MCKENNA AND HARRISON INC. (CA) | 1981-09-02 | — | — | EP | claimed |
| US-3985726-A | DYEING AND PRINTING LEATHER, WOOL, SILK AND SYNTHETIC FIBERS | CIBA-GEIGY AG (CH) | 1976-10-12 | — | — | US | claimed |
| US-3971740-A | DYES FOR POLYESTER FIBERS | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | claimed |
| CN-109843965-B | Epoxy resin composition for forming printed wiring board | 日产化学株式会社 | 2021-07-27 | — | — | CN | disclosed |
| CN-105431751-B | Vinyl alcohol system polymer film | 株式会社可乐丽 | 2018-04-06 | — | — | CN | disclosed |
| US-3945989-A | Fluoro triazine containing water insoluble azo dyestuff | CIBA-GEIGY AG (CH) | 1976-03-23 | — | — | US | disclosed |
| US-3933786-A | Heterocyclic-azo-phenyl compounds containing a styrl group | CIBA-GEIGY AG (CH) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010056206-A1 | PROCESS FOR THE PREPARATION OF IOPAMIDOL | ITPA, ITPR3, PPIP5K2 | TDP1 1265/4885TSHR 1147/4885ALDH1A1 3966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.