Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 7/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3578962 | 0.87 | CCR1 (0.37) | CCR9CCR2SERPINE1KDM4EALDH1A1 | |
| SCHEMBL3574965 | 0.86 | ALDH1A1 (0.38) | CCR9CCR2SERPINE1KDM4EALDH1A1 | |
| SCHEMBL3577510 | 0.85 | SERPINE1 (0.36) | CCR9CCR2SERPINE1KDM4EALDH1A1 | |
| SCHEMBL3576392 | 0.82 | HCRTR1 (0.38) | CCR9CCR2SERPINE1KDM4EALDH1A1 | |
| SCHEMBL3580080 | 0.81 | KLKB1 (0.36) | CCR9CCR2SERPINE1KDM4EALDH1A1 | |
| SCHEMBL3582314 | 0.80 | CCR9 (0.38) | CCR9CCR2SERPINE1LMNAHTT | |
| SCHEMBL3575609 | 0.78 | LMNA (0.43) | SERPINE1LMNASMN1; SMN2 | |
| SCHEMBL3584396 | 0.78 | C5AR1 (0.44) | CCR9CCR2SERPINE1KDM4EALDH1A1 | |
| SCHEMBL3581366 | 0.77 | HCRTR1 (0.38) | CCR9CCR2SERPINE1KDM4EALDH1A1 | |
| SCHEMBL3576868 | 0.77 | HCRTR1 (0.42) | CCR9SERPINE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |