Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 13/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580812 | 0.89 | TRPM8 (0.35) | CCR9KDM4CLMNAHTTKCNH2 | |
| SCHEMBL3576392 | 0.87 | HCRTR1 (0.38) | CCR9CCR2SERPINE1LMNAHTT | |
| SCHEMBL3574965 | 0.84 | ALDH1A1 (0.38) | CCR9CCR2SERPINE1 | |
| SCHEMBL3577510 | 0.83 | SERPINE1 (0.36) | CCR9CCR2SERPINE1LMNAHTT | |
| SCHEMBL3580080 | 0.83 | KLKB1 (0.36) | CCR9CCR2SERPINE1LMNAHTT | |
| SCHEMBL3578962 | 0.80 | CCR1 (0.37) | CCR9CCR2SERPINE1LMNASMN1; SMN2 | |
| SCHEMBL3577474 | 0.80 | CCR9 (0.35) | CCR9CCR2SERPINE1LMNAHTT | |
| SCHEMBL3581537 | 0.80 | PTGER2 (0.42) | CCR9 | |
| SCHEMBL3576868 | 0.80 | HCRTR1 (0.42) | CCR9SERPINE1F10TRPM8 | |
| SCHEMBL3581366 | 0.80 | HCRTR1 (0.38) | CCR9CCR2SERPINE1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |