Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 10/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.33 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3574969 | 0.93 | C5AR1 (0.39) | C5AR1F10KLKB1CA12CA1 | |
| SCHEMBL3581176 | 0.89 | SLC2A1 (0.38) | MEN1KMT2ASLC2A1 | |
| SCHEMBL3571491 | 0.88 | C5AR1 (0.42) | C5AR1F10KLKB1CA12CA1 | |
| SCHEMBL3581889 | 0.84 | C5AR1 (0.40) | C5AR1F10KLKB1MEN1KMT2A | |
| SCHEMBL3580029 | 0.84 | MLYCD (0.34) | C5AR1MLYCDHSP90AA1 | |
| SCHEMBL3571528 | 0.83 | TP53 (0.41) | C5AR1F10MEN1KMT2AHSP90AA1 | |
| SCHEMBL3586383 | 0.83 | NLRP3 (0.39) | C5AR1F10CA12CA1CA2 | |
| SCHEMBL3575504 | 0.82 | SLC2A1 (0.38) | MEN1KMT2ASLC2A1 | |
| SCHEMBL3579370 | 0.81 | SLC2A1 (0.39) | MEN1KMT2ASLC2A1 | |
| SCHEMBL3574044 | 0.81 | NR1H4 (0.37) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |