Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.32 |
| ▸ | CENPE | Q02224 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | LIPC | P11150 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3574969 | 0.91 | C5AR1 (0.39) | MLYCDHSP90AA1C5AR1 | |
| SCHEMBL3574044 | 0.90 | NR1H4 (0.37) | SIGMAR1HSP90AA1OPRM1OPRD1 | |
| SCHEMBL3575504 | 0.89 | SLC2A1 (0.38) | TRPV1CYP2C19 | |
| SCHEMBL3574238 | 0.85 | MLYCD (0.35) | MLYCDSIGMAR1HSP90AA1OPRM1OPRD1 | |
| SCHEMBL3577889 | 0.84 | C5AR1 (0.39) | MLYCDHSP90AA1C5AR1 | |
| SCHEMBL1397709 | 0.83 | OPRM1 (0.35) | SIGMAR1OPRM1OPRD1RAF1MAP2K1 | |
| SCHEMBL3584062 | 0.83 | GBA1 (0.34) | MLYCDSIGMAR1HSP90AA1OPRM1OPRD1 | |
| SCHEMBL3581176 | 0.82 | SLC2A1 (0.38) | TRPV1CYP2C19 | |
| SCHEMBL3584245 | 0.82 | SIGMAR1 (0.34) | SIGMAR1OPRM1OPRD1CYP2C19LIPG | |
| SCHEMBL3579370 | 0.81 | SLC2A1 (0.39) | TRPV1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |