SCHEMBL357801

SCHEMBL357801

NC(=O)NCc1ccccn1

nearest known ligand 0.73

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.73
NPC1 O15118 3/20 0.61
RAB9A P51151 3/20 0.61
POLB P06746 3/20 0.61
ALDH1A1 P00352 4/20 0.59
KDM4E B2RXH2 1/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
GAA P10253 1/20 0.59
HPGD P15428 3/20 0.58
ALOX15 P16050 2/20 0.58
TDP1 Q9NUW8 1/20 0.58
LMNA P02545 1/20 0.58
P2RX7 Q99572 1/20 0.56
CA2 P00918 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27694741 0.98 SMN1; SMN2 (0.71) SMN1; SMN2NPC1RAB9APOLBALDH1A1
Acetic Acid SCHEMBL6261851 0.92 SMN1; SMN2 (0.63) SMN1; SMN2NPC1RAB9APOLBALDH1A1
Acetic Acid SCHEMBL6262675 0.92 SMN1; SMN2 (0.63) SMN1; SMN2NPC1RAB9APOLBALDH1A1
SCHEMBL31558918 0.86 SMN1; SMN2 (0.80) SMN1; SMN2NPC1RAB9APOLBALDH1A1
SCHEMBL7977040 0.85 SMN1; SMN2 (0.73) SMN1; SMN2NPC1RAB9APOLBALDH1A1
SCHEMBL29460273 0.85 SMN1; SMN2 (0.79) SMN1; SMN2NPC1RAB9APOLBALDH1A1
SCHEMBL18415475 0.85 SMN1; SMN2 (1.00) SMN1; SMN2NPC1RAB9APOLBALDH1A1
SCHEMBL21065524 0.85 SMN1; SMN2 (0.79) SMN1; SMN2NPC1RAB9APOLBALDH1A1
SCHEMBL30522589 0.85 SMN1; SMN2 (1.00) SMN1; SMN2NPC1RAB9APOLBALDH1A1
SCHEMBL11096788 0.84 SMN1; SMN2 (0.61) SMN1; SMN2NPC1RAB9APOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260028333-A1 NEW COMPOUNDS VICORE PHARMA AB (SE) 2026-01-29 US claimed
US-20220388994-A1 NEW COMPOUNDS VICORE PHARMA AB (SE) 2022-12-08 US claimed
CN-115109049-A Triazine compound containing aryl urea structure and application thereof 江西科技师范大学 2022-09-27 CN claimed
EP-4031240-A1 NEW COMPOUNDS Vicore Pharma AB (SE) 2022-07-27 EP claimed
CN-114786774-A Novel compounds 维科尔药物公司 2022-07-22 CN claimed
US-20160369208-A1 UREA GELLANT THE PROCTER & GAMBLE COMPANY 2016-12-22 US claimed
CN-101981047-A Novel lupane derivatives VIROCHEM PHARMA INC 2011-02-23 CN claimed
EP-1725238-A4 M 3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LTD (GB) 2009-04-01 EP claimed
EP-1725238-A2 M 3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2006-11-29 EP claimed
WO-2005094251-A2 M3MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS GLAXO GROUP LIMITED (GB) 2005-10-13 WO claimed
US-5096978-A Butadiene polymers having improved scorch delay and fast cure rates; tires; treads MONSANTO COMPANY (US) 1992-03-17 US claimed
EP-0364428-A1 Vulcanizable synthetic rubber compositions cure-activated by substituted ureas Monsanto Company (US) 1990-04-18 EP claimed
EP-4746880-A2 METHODS OF TREATING DILATED CARDIOMYOPATHY Regencor, Inc. (US) 2026-05-27 EP disclosed
US-20260028333-A1 NEW COMPOUNDS VICORE PHARMA AB (SE) 2026-01-29 US disclosed
US-20250304576-A1 IKK INHIBITORS CANCER RESEARCH TECH LTD (GB) 2025-10-02 US disclosed
WO-2025024320-A2 METHODS OF TREATING DILATED CARDIOMYOPATHY REGENCOR, INC. (US) 2025-01-30 WO disclosed
EP-0934296-A1 CHROMAN DERIVATIVES NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1999-08-11 EP disclosed
WO-1998004542-A1 CHROMAN DERIVATIVES NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1998-02-05 WO disclosed
US-5096978-A Butadiene polymers having improved scorch delay and fast cure rates; tires; treads MONSANTO COMPANY (US) 1992-03-17 US disclosed
EP-0364428-A1 Vulcanizable synthetic rubber compositions cure-activated by substituted ureas Monsanto Company (US) 1990-04-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028333-A1 NEW COMPOUNDS AGTR1, AGTR2, REN SMN1; SMN2 4062/4885NPC1 897/4885RAB9A 1808/4885
US-20220388994-A1 NEW COMPOUNDS RXFP3, RXFP4, RXFP1 SMN1; SMN2 4226/4885NPC1 2981/4885RAB9A 982/4885
US-20250304576-A1 IKK INHIBITORS NFKBIA, IKBKE, IKBKB SMN1; SMN2 3836/4885NPC1 1965/4885RAB9A 2770/4885
US-20160369208-A1 UREA GELLANT UGP2, UGGT1, SLC14A1 SMN1; SMN2 4419/4885NPC1 1374/4885RAB9A 2575/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.