Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667892 | 0.86 | ALDH1A1 (0.49) | ALDH1A1MAPK1MAPTLMNASMN1; SMN2 | |
| SCHEMBL22897785 | 0.85 | MAPT (0.55) | ALDH1A1MAPK1MAPTLMNASMN1; SMN2 | |
| SCHEMBL8842467 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MAPK1MAPTLMNASMN1; SMN2 | |
| SCHEMBL3823448 | 0.82 | ALDH1A1 (0.54) | ALDH1A1MAPK1MAPTLMNASMN1; SMN2 | |
| SCHEMBL28712089 | 0.81 | ALDH1A1 (0.53) | ALDH1A1MAPK1MAPTLMNASMN1; SMN2 | |
| SCHEMBL257715 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPK1MAPTLMNASMN1; SMN2 | |
| SCHEMBL177095 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPK1MAPTLMNASMN1; SMN2 | |
| SCHEMBL5219494 | 0.80 | ALDH1A1 (0.52) | ALDH1A1MAPK1MAPTLMNASMN1; SMN2 | |
| SCHEMBL29495085 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPK1MAPTLMNASMN1; SMN2 | |
| SCHEMBL430628 | 0.80 | ALDH1A1 (0.51) | ALDH1A1MAPK1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3920702-B1 | PESTICIDAL COMPOSITIONS AND METHODS | CORTEVA AGRISCIENCE LLC (US) | 2024-09-11 | — | — | EP | disclosed |
| CN-113347883-B | Pesticidal compositions and methods | 科迪华农业科技有限责任公司 | 2023-11-03 | — | — | CN | disclosed |
| US-11332452-B2 | Pesticidal compositions and methods | CORTEVA AGRISCIENCE LLC (US) | 2022-05-17 | — | — | US | disclosed |
| US-11332452-B2 | Pesticidal compositions and methods | CORTEVA AGRISCIENCE LLC (US) | 2022-05-17 | — | — | US | disclosed |
| EP-3920702-A1 | PESTICIDAL COMPOSITIONS AND METHODS | Corteva Agriscience LLC (US) | 2021-12-15 | — | — | EP | disclosed |
| US-20210276963-A1 | PESTICIDAL COMPOSITIONS AND METHODS | DOW AGROSCIENCES LLC (US) | 2021-09-09 | — | — | US | disclosed |
| US-20210276963-A1 | PESTICIDAL COMPOSITIONS AND METHODS | DOW AGROSCIENCES LLC (US) | 2021-09-09 | — | — | US | disclosed |
| CN-113347883-A | Pesticidal compositions and methods | 科迪华农业科技有限责任公司 | 2021-09-03 | — | — | CN | disclosed |
| WO-2020163146-A1 | PESTICIDAL COMPOSITIONS AND METHODS | DOW AGROSCIENCES LLC (US) | 2020-08-13 | — | — | WO | disclosed |
| WO-2020163146-A1 | PESTICIDAL COMPOSITIONS AND METHODS | DOW AGROSCIENCES LLC (US) | 2020-08-13 | — | — | WO | disclosed |
| EP-2118076-B1 | QUINOXALINE COMPOUNDS AND USE THEREOF | MERCK SERONO SA (CH) | 2019-09-04 | — | — | EP | disclosed |
| EP-2118076-B1 | QUINOXALINE COMPOUNDS AND USE THEREOF | MERCK SERONO SA (CH) | 2019-09-04 | — | — | EP | disclosed |
| US-8614215-B2 | Quinoxaline inhibitors of phosphoinositide-3-kinases (PI3Ks) | MERCK SERONO SA (CH) | 2013-12-24 | — | — | US | disclosed |
| US-20100137308-A1 | Quinoxaline Compounds and Use Thereof | MERCK SERONO SA (CH) | 2010-06-03 | — | — | US | disclosed |
| US-20100137308-A1 | Quinoxaline Compounds and Use Thereof | MERCK SERONO SA (CH) | 2010-06-03 | — | — | US | disclosed |
| US-20100137308-A1 | Quinoxaline Compounds and Use Thereof | MERCK SERONO SA (CH) | 2010-06-03 | — | — | US | disclosed |
| WO-2008101979-A1 | QUINOXALINE COMPOUNDS AND USE THEREOF | MERCK SERONO S.A. (CH) | 2008-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137308-A1 | Quinoxaline Compounds and Use Thereof | PFKP, PDXK, PF4 | ALDH1A1 577/4885MAPK1 2681/4885GABRA1 2532/4885 |
| US-20210276963-A1 | PESTICIDAL COMPOSITIONS AND METHODS | ACHE, DDT, PLA2G2D | ALDH1A1 762/4885MAPK1 3841/4885GABRA1 2307/4885 |
| US-11332452-B2 | Pesticidal compositions and methods | ACHE, DDT, PLA2G2D | ALDH1A1 762/4885MAPK1 3841/4885GABRA1 2307/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.