SCHEMBL472879

SCHEMBL472879

CNC(=O)c1ccc(C(N)=O)c2c1CCCCC2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.43
ALOX15 P16050 3/20 0.43
HSD17B10 Q99714 3/20 0.43
KDM4E B2RXH2 3/20 0.43
MAPT P10636 3/20 0.43
HPGD P15428 3/20 0.43
KMT2A Q03164 3/20 0.43
CASP1 P29466 2/20 0.43
CASP7 P55210 2/20 0.43
TSHR P16473 2/20 0.43
MEN1 O00255 2/20 0.43
NEU3 Q9UQ49 1/20 0.38
MAPK1 P28482 1/20 0.38
USP2 O75604 1/20 0.38
RECQL P46063 1/20 0.38
FLT3 P36888 3/20 0.37
POLB P06746 2/20 0.37
PKM P14618 1/20 0.37
LMNA P02545 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4556902 0.85 HSD17B10 (0.46) ALDH1A1ALOX15HSD17B10KDM4EMAPT
SCHEMBL5459284 0.85 HSD17B10 (0.46) ALDH1A1ALOX15HSD17B10KDM4EMAPT
SCHEMBL8708889 0.85 HSD17B10 (0.46) ALDH1A1ALOX15HSD17B10KDM4EMAPT
SCHEMBL16739249 0.85 HSD17B10 (0.46) ALDH1A1ALOX15HSD17B10KDM4EMAPT
SCHEMBL35972 0.85 HSD17B10 (0.46) ALDH1A1ALOX15HSD17B10KDM4EMAPT
SCHEMBL919063 0.85 HSD17B10 (0.46) ALDH1A1ALOX15HSD17B10KDM4EMAPT
SCHEMBL35787 0.85 HSD17B10 (0.46) ALDH1A1ALOX15HSD17B10KDM4EMAPT
SCHEMBL1160668 0.83 HSD17B10 (0.47) ALDH1A1ALOX15HSD17B10KDM4EMAPT
SCHEMBL8295144 0.75 ADRA1A (0.45) ALDH1A1HSD17B10KDM4EHPGDKMT2A
SCHEMBL10468834 0.75 CXCR5 (0.56) ALDH1A1KDM4EKMT2ATSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1647731-B1 Clutch release mechanism for a motor vehicle gear shift clutch SCHAEFFLER TECHNOLOGIES AG (DE) 2013-03-13 EP claimed
EP-1891347-B1 RELEASE BEARING OF A DISCONNECT CLUTCH SCHAEFFLER KG (DE) 2009-07-15 EP claimed
EP-1389514-B2 TABLET, PROCESS FOR PRODUCING THE SAME, AND MOLDED ARTICLE OBTAINED THEREFROM TORAY INDUSTRIES (JP) 2015-11-04 EP disclosed
WO-2014063114-A1 ANTI-CORROSION COMPOSITIONS VORBECK MATERIALS (US) 2014-04-24 WO disclosed
EP-1389514-B1 TABLET, PROCESS FOR PRODUCING THE SAME, AND MOLDED ARTICLE OBTAINED THEREFROM TORAY INDUSTRIES (JP) 2012-02-01 EP disclosed
US-7514144-B2 Tablet, process for producing the same, and molded article obtained therefrom TORAY INDUSTRIES, INC. (JP) 2009-04-07 US disclosed
EP-1971642-A1 CARBON FIBER REINFORCED POLYAMIDE RESIN COMPOSITION E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-09-24 EP disclosed
WO-2007061965-A1 CARBON FIBER REINFORCED POLYAMIDE RESIN COMPOSITION E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-05-31 WO disclosed
US-20050098916-A1 Tablet, process for producing the same, and molded article obtained therefrom TORAY INDUSTRIES, INC., A CORPORATION OF JAPAN (JP) 2005-05-12 US disclosed
EP-1389514-A1 TABLET, PROCESS FOR PRODUCING THE SAME, AND MOLDED ARTICLE OBTAINED THEREFROM TORAY INDUSTRIES, INC. (JP) 2004-02-18 EP disclosed
EP-0926175-B1 Liquid-crystalline resin and thermoplastic resin composition containing the liquid-crystalline resin TORAY INDUSTRIES (JP) 2003-10-08 EP disclosed
US-6046300-A LIQUID CRYSTALLINE RESIN HAVING ESTER BONDS, WHICH HAS A SPECIFIC HYDROXYL TERMINAL CONCENTRATION; METHOD OF MAKING BY TREATING CONVENTIONAL POLYESTER TO DEACETYLING POLYCONDENSATION; FIBERS, FILMS AND MOLDINGS; HIGH STRENGTH TORAY INDUSTRIES, INC. (JP) 2000-04-04 US disclosed
EP-0926175-A2 Liquid-crystalline resin and thermoplastic resin composition containing the liquid-crystalline resin TORAY INDUSTRIES, INC. (JP) 1999-06-30 EP disclosed