Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14037658 | 0.80 | CYP19A1 (0.47) | LMNATSHRCYP2C19 | |
| SCHEMBL24126788 | 0.75 | ELANE (0.56) | MEN1KMT2ACYP2C19GAA | |
| SCHEMBL11882626 | 0.73 | CYP2C19 (0.60) | ALDH1A1LMNACA1CA2ALDH3A1 | |
| SCHEMBL5334247 | 0.73 | ALDH1A1 (0.51) | ALDH1A1KMT2A | |
| SCHEMBL8293499 | 0.73 | CYP19A1 (0.41) | ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL14359249 | 0.71 | CYP19A1 (0.42) | HTR2C | |
| SCHEMBL14359304 | 0.70 | HTR1A (0.44) | HTR2CKDM4EMEN1KMT2AUSP2 | |
| SCHEMBL12336004 | 0.69 | ALDH1A1 (0.59) | ALDH1A1LMNACA1CA2ALDH3A1 | |
| SCHEMBL10971341 | 0.69 | HTR1A (0.68) | ALDH1A1CYP2D6HTR2CKCNH2KDM4E | |
| Methsuximide SCHEMBL34852 | 0.69 | CYP19A1 (0.70) | ALDH1A1LMNATSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9016221-B2 | Surface topographies for non-toxic bioadhesion control | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2015-04-28 | — | — | US | claimed |
| US-8853257-B2 | Succinimide derivatives as ocular hypotensive agents | SHARIR MORDECHAI (IL) | 2014-10-07 | — | — | US | claimed |
| EP-1951229-B1 | SUCCINIMIDE DERIVATIVES AS OCULAR HYPOTENSIVE AGENTS | SHARIR MORDECHAI (IL) | 2013-07-10 | — | — | EP | claimed |
| US-20120016001-A1 | SUCCINIMIDE DERIVATIVES AS OCULAR HYPOTENSIVE AGENTS | SHARIR MORDECHAI (IL) | 2012-01-19 | — | — | US | claimed |
| US-20100226943-A1 | SURFACE TOPOGRAPHIES FOR NON-TOXIC BIOADHESION CONTROL | UNIVERSITY OF FLORIDA (US) | 2010-09-09 | — | — | US | claimed |
| US-20090318515-A1 | SUCCINIMIDE DERIVATIVES AS OCULAR HYPOTENSIVE AGENTS | SHARIR MORDECHAI | 2009-12-24 | — | — | US | claimed |
| CN-101500558-A | Succinimide derivatives as ocular hypotensive agents | MORDECHAI SHARIR (IL) | 2009-08-05 | — | — | CN | claimed |
| CN-101330905-A | Freeze-drying process and products obtained thereby | SCIDOSE LLC (US) | 2008-12-24 | — | — | CN | claimed |
| EP-1954244-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | Scidose, Llc (US) | 2008-08-13 | — | — | EP | claimed |
| EP-1951229-A2 | SUCCINIMIDE DERIVATIVES AS OCULAR HYPOTENSIVE AGENTS | Sharir, Mordechai (IL) | 2008-08-06 | — | — | EP | claimed |
| WO-2007061529-A1 | LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY | SCIDOSE LLC. (US) | 2007-05-31 | — | — | WO | claimed |
| WO-2007057889-A2 | SUCCINIMIDE DERIVATIVES AS OCULAR HYPOTENSIVE AGENTS | SHARIR MORDECHAI (IL) | 2007-05-24 | — | — | WO | claimed |
| US-20070116729-A1 | Lyophilization process and products obtained thereby | SCIDOSE LLC | 2007-05-24 | — | — | US | claimed |
| WO-2025129358-A1 | STABLE FILM FORMULATIONS FOR HIGH LOADING OF LOW MELTING POINT ACTIVES | INTELGENX CORP. (CA) | 2025-06-26 | — | — | WO | disclosed |
| CN-119823266-A | Tumor microenvironment specific activation of CD47 antibodies | 英脉德医疗科技(广东)有限公司 | 2025-04-15 | — | — | CN | disclosed |
| US-20220047505-A1 | Controlled Absorption Water-Soluble Pharmaceutically Active Organic Compound Formulation for Once-Daily Administration | STI PHARMA, LLC (US) | 2022-02-17 | — | — | US | disclosed |
| US-6331289-B1 | ULTRASOUND CONTRAST AGENTS, SUSPENSION IN AQUEOUS CARRIER LIQUID OF A REPORTER COMPRISING GAS-CONTAINING OR GAS-GENERATING MATERIAL, AGENT CAPABLE OF FORMING AT LEAST TWO TYPES OF BINDING PAIRS WITH TARGET; REPORTER BEING CONJUGATED | NYCOMED IMAGING AS (NO) | 2001-12-18 | — | — | US | disclosed |
| US-6264917-B1 | MIXTURE OF GAS FILLED MICROBUBBLES AND RELEASING AGENT | NYCOMED IMAGING AS (NO) | 2001-07-24 | — | — | US | disclosed |
| US-6261537-B1 | TARGETS AND ULTRASOUND DIAGNOSIS OF ACTIVE MATERIALS, AQUEOUS CARRIER LIQUIDS, CARRIERS AND FILM FORMING SURFACTANT PHOSPHATIDES | NYCOMED IMAGING AS (NO) | 2001-07-17 | — | — | US | disclosed |
| US-4188398-A | PARA-ISOPROPOXYPHENYLSUCCINIMIDE | AKOPIAN NINA E | 1980-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016001-A1 | SUCCINIMIDE DERIVATIVES AS OCULAR HYPOTENSIVE AGENTS | SUCNR1, SYNGR2, SDHA | ALDH1A1 803/4885LMNA 2568/4885CA1 650/4885 |
| US-20090318515-A1 | SUCCINIMIDE DERIVATIVES AS OCULAR HYPOTENSIVE AGENTS | SUCNR1, TNNI3, STIM1 | ALDH1A1 975/4885LMNA 2205/4885CA1 2134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.