Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PON1 | P27169 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL2936298 | 0.94 | FDPS (0.46) | FDPSSMN1; SMN2MEN1HSP90AA1KMT2A | |
| Acetic Acid SCHEMBL28506136 | 0.93 | FDPS (0.43) | FDPSSMN1; SMN2MEN1HSP90AA1KMT2A | |
| Acetic Acid SCHEMBL302143 | 0.92 | FDPS (0.45) | FDPSSMN1; SMN2MEN1HSP90AA1KMT2A | |
| Bicarbonate SCHEMBL15404411 | 0.92 | FDPS (0.45) | FDPSSMN1; SMN2MEN1HSP90AA1KMT2A | |
| Oxalic Acid SCHEMBL29142284 | 0.91 | FDPS (0.42) | FDPSSMN1; SMN2MEN1HSP90AA1KMT2A | |
| Glycolic Acid SCHEMBL2536925 | 0.91 | FDPS (0.44) | FDPSSMN1; SMN2MEN1HSP90AA1KMT2A | |
| Propionic Acid SCHEMBL508030 | 0.91 | FDPS (0.44) | FDPSSMN1; SMN2MEN1HSP90AA1KMT2A | |
| Oxalic Acid SCHEMBL17710444 | 0.91 | SMN1; SMN2 (0.47) | FDPSSMN1; SMN2MEN1HSP90AA1KMT2A | |
| Acetic Acid SCHEMBL28802050 | 0.90 | SMN1; SMN2 (0.46) | FDPSSMN1; SMN2MEN1HSP90AA1KMT2A | |
| Cadaverine Tartrate SCHEMBL3680530 | 0.90 | FDPS (0.44) | FDPSSMN1; SMN2MEN1HSP90AA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3275039-B1 | ELECTROLYTES AND METAL HYDRIDE BATTERIES | BASF CORP (US) | 2025-08-27 | — | — | EP | claimed |
| CN-119661373-A | TATB crystal with fusiform micro-nano hierarchical structure and preparation method thereof | 中国工程物理研究院化工材料研究所 | 2025-03-21 | — | — | CN | claimed |
| CN-114456019-B | Porous TATB explosive spherulite and preparation method thereof | 中国工程物理研究院化工材料研究所 | 2022-11-15 | — | — | CN | claimed |
| CN-107710462-B | Electrochemical hydrogen storage electrode and battery | 巴斯夫公司 | 2022-08-02 | — | — | CN | claimed |
| CN-113683780-B | Antiserum and low-cytotoxicity polyamino acid gene delivery carrier material with membrane penetrating activity and nucleus positioning function | 广州医科大学 | 2022-07-05 | — | — | CN | claimed |
| CN-114456019-A | Porous TATB explosive spherulite and preparation method thereof | 中国工程物理研究院化工材料研究所 | 2022-05-10 | — | — | CN | claimed |
| CN-113683780-A | Antiserum and low-cytotoxicity polyamino acid gene delivery carrier material with membrane penetrating activity and nucleus positioning function | 广州医科大学 | 2021-11-23 | — | — | CN | claimed |
| US-20160365228-A1 | COMPONENT OF A PLASMA PROCESSING APPARATUS HAVING A PROTECTIVE IN SITU FORMED LAYER ON A PLASMA EXPOSED SURFACE | LAM RESEARCH CORPORATION | 2016-12-15 | — | — | US | claimed |
| US-9449797-B2 | Component of a plasma processing apparatus having a protective in situ formed layer on a plasma exposed surface | LAM RESEARCH CORPORATION (US) | 2016-09-20 | — | — | US | claimed |
| US-20140335698-A1 | COMPONENT OF A PLASMA PROCESSING APPARATUS HAVING A PROTECTIVE IN SITU FORMED LAYER ON A PLASMA EXPOSED SURFACE | LAM RESEARCH CORPORATION (US) | 2014-11-13 | — | — | US | claimed |
| EP-4739742-A1 | LATENT CATALYST AND COATING COMPOSITIONS INCLUDING THE SAME | SWIMC LLC (US) | 2026-05-13 | — | — | EP | disclosed |
| US-12559586-B2 | Compositions containing uretdione groups crosslinking at low temperatures | COVESTRO DEUTSCHLAND AG (DE) | 2026-02-24 | — | — | US | disclosed |
| EP-3275039-B1 | ELECTROLYTES AND METAL HYDRIDE BATTERIES | BASF CORP (US) | 2025-08-27 | — | — | EP | disclosed |
| US-12291506-B2 | Method for producing amidate compound, and amidate compound | KOEI CHEMICAL COMPANY, LIMITED (JP) | 2025-05-06 | — | — | US | disclosed |
| CN-119661373-A | TATB crystal with fusiform micro-nano hierarchical structure and preparation method thereof | 中国工程物理研究院化工材料研究所 | 2025-03-21 | — | — | CN | disclosed |
| US-20140335698-A1 | COMPONENT OF A PLASMA PROCESSING APPARATUS HAVING A PROTECTIVE IN SITU FORMED LAYER ON A PLASMA EXPOSED SURFACE | LAM RESEARCH CORPORATION (US) | 2014-11-13 | — | — | US | disclosed |
| EP-2684872-A1 | COMPOUND HAVING HEPTAMETHINE STRUCTURE, SENSITIZING DYE AND PHOTOELECTRIC CONVERSION ELEMENT | Gifu University (JP) | 2014-01-15 | — | — | EP | disclosed |
| US-20140005415-A1 | IMMOBILIZATION OF IONIC LIQUIDS VIA MECHNOCHEMICAL INTERCALATION IN LAYERED MATERIALS | TEXAS STATE UNIVERSITY-SAN MARCOS (US) | 2014-01-02 | — | — | US | disclosed |
| US-20120011886-A1 | IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS | E. I. DU PONT DE NEMOURS AND COMPANY | 2012-01-19 | — | — | US | disclosed |
| WO-2011091131-A2 | ESLICARBAZEPINE ACETATE AND ITS POLYMORPHS | DR. REDDY'S LABORATORIES LTD. (IN) | 2011-07-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12559586-B2 | Compositions containing uretdione groups crosslinking at low temperatures | URB2, UQCRB, UQCRC2 | FDPS 3376/4885SMN1; SMN2 4159/4885MEN1 2202/4885 |
| US-12291506-B2 | Method for producing amidate compound, and amidate compound | NAAA, NIT2, PAM | FDPS 299/4885SMN1; SMN2 3051/4885MEN1 55/4885 |
| US-20140005415-A1 | IMMOBILIZATION OF IONIC LIQUIDS VIA MECHNOCHEMICAL INTERCALATION IN LAYERED MATERIALS | CALCOCO2, MCOLN2, MECP2 | FDPS 4374/4885SMN1; SMN2 2660/4885MEN1 689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.