SCHEMBL3580053

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22359167	0.90	SMN1; SMN2 (0.46)	SMN1; SMN2CACNA2D1CACNA1BCACNB1GBA1
	SCHEMBL30584851	0.90	SMN1; SMN2 (0.50)	SMN1; SMN2CACNA2D1CACNA1BCACNB1GAA
	Hydrochloric Acid SCHEMBL30584820	0.89	SMN1; SMN2 (0.49)	SMN1; SMN2CACNA2D1CACNA1BCACNB1GAA
	SCHEMBL4035398	0.87	SMN1; SMN2 (0.62)	SMN1; SMN2GAAJAK2JAK1TYK2
	Hydrochloric Acid SCHEMBL27659724	0.85	SMN1; SMN2 (0.60)	SMN1; SMN2GAAJAK2JAK1TYK2
	SCHEMBL22358971	0.84	GBA1 (0.49)	SMN1; SMN2CACNA2D1CACNA1BCACNB1GBA1
	SCHEMBL4732821	0.84	SMN1; SMN2 (0.58)	SMN1; SMN2GAAJAK2JAK1TYK2
	SCHEMBL25134096	0.83	SMN1; SMN2 (0.45)	SMN1; SMN2CACNA2D1CACNA1BCACNB1GBA1
	Hydrochloric Acid SCHEMBL28764245	0.81	SMN1; SMN2 (0.63)	SMN1; SMN2GAAACHEHTR4KDM4E
	SCHEMBL1438737	0.79	SMN1; SMN2 (0.53)	SMN1; SMN2GBA1GAAJAK2JAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.