Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GRM8 | O00222 | 1/20 | 0.33 |
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25929681 | 0.88 | SLC1A2 (0.40) | SLC1A2SLC1A1APLNRLMNAGRM2 | |
| SCHEMBL9011285 | 0.84 | G6PD (0.30) | — | |
| SCHEMBL11063629 | 0.79 | ATM (0.37) | CYP1A2CYP2C19TSHRPOLB | |
| SCHEMBL9141620 | 0.73 | GRM4 (0.34) | SLC1A2SLC1A1LMNAGRM2GRM3 | |
| SCHEMBL22941787 | 0.73 | GRM4 (0.34) | SLC1A2SLC1A1LMNAGRM2GRM3 | |
| SCHEMBL1151609 | 0.73 | APLNR (0.34) | SLC1A2SLC1A1APLNRHSD11B1 | |
| SCHEMBL5925394 | 0.72 | GRM2 (0.33) | SLC1A2SLC1A1LMNAGRM2GRM3 | |
| SCHEMBL15440623 | 0.72 | GRM4 (0.37) | SLC1A2SLC1A1LMNAGRM2GRM3 | |
| SCHEMBL7079218 | 0.72 | GRM2 (0.33) | SLC1A2SLC1A1LMNAGRM2GRM3 | |
| SCHEMBL76019 | 0.72 | GRM4 (0.37) | SLC1A2SLC1A1LMNAGRM2GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2977373-B1 | METHOD FOR THE CATALYTIC PRODUCTION OF ESTERS | EVONIK DEGUSSA GMBH (DE) | 2017-10-25 | — | — | EP | disclosed |
| US-9605001-B2 | Production of polyketides and other natural products | BUCK INSTITUTE FOR RESEARCH ON AGING (US) | 2017-03-28 | — | — | US | disclosed |
| EP-3030544-A1 | METHOD FOR THE SYNTHESIS OF SATURATED CARBOXYLIC ACID ESTERS | Evonik Degussa GmbH (DE) | 2016-06-15 | — | — | EP | disclosed |
| EP-2977373-A1 | METHOD FOR THE CATALYTIC PRODUCTION OF ESTERS | Evonik Degussa GmbH (DE) | 2016-01-27 | — | — | EP | disclosed |
| US-20150266896-A1 | PRODUCTION OF POLYKETIDES AND OTHER NATURAL PRODUCTS | BIOTICA TECH LTD (GB) | 2015-09-24 | — | — | US | disclosed |
| EP-1521828-B1 | PRODUCTION OF POLYKETIDES | BUCK INST FOR RES ON AGING (US) | 2015-07-01 | — | — | EP | disclosed |
| WO-2015018845-A1 | METHOD FOR THE SYNTHESIS OF SATURATED CARBOXYLIC ACID ESTERS | LEIBNIZ-INSTITUT FÜR KATALYSE E.V. AN DER UNIVERSITÄT ROSTOCK (DE) | 2015-02-12 | — | — | WO | disclosed |
| US-7645768-B2 | Production of polyketides and other natural products | WYETH (US) | 2010-01-12 | — | — | US | disclosed |
| CN-100569944-C | Production of polyketides and other natural products | BIOTICA TECH LTD (GB) | 2009-12-16 | — | — | CN | disclosed |
| US-20080287482-A1 | Production of Polyketides and Other Natural Products | GREGORY MATTHEW ALAN | 2008-11-20 | — | — | US | disclosed |
| CN-101302225-A | Production of polyketides and other natural products | BIOTICA TECH LTD (GB) | 2008-11-12 | — | — | CN | disclosed |
| EP-1967520-A2 | Production of polyketides and other natural products | Biotica Technology Limited (GB) | 2008-09-10 | — | — | EP | disclosed |
| US-7390895-B2 | Production of polyketides and other natural products | BIOTICA TECHNOLOGY LIMITED (GB) | 2008-06-24 | — | — | US | disclosed |
| US-20080039486-A1 | PRODUCTION OF POLYKETIDES AND OTHER NATURAL PRODUCTS | GREGORY MATTHEW A | 2008-02-14 | — | — | US | disclosed |
| US-20080021211-A1 | PRODUCTION OF POLYKETIDES AND OTHER NATURAL PRODUCTS | BIOTICA TECHNOLOGY LIMITED (GB) | 2008-01-24 | — | — | US | disclosed |
| EP-1589031-B1 | Production of polyketides and other natural products | BIOTICA TECH LTD (GB) | 2007-08-15 | — | — | EP | disclosed |
| EP-1655372-A2 | Production of polyketides and other natural products | Biotica Technology Limited (GB) | 2006-05-10 | — | — | EP | disclosed |
| US-20060078980-A1 | Production of polyketides and other natural products | GREGORY MATTHEW A | 2006-04-13 | — | — | US | disclosed |
| EP-1589031-A2 | Production of polyketides and other natural products | Biotica Technology Limited (GB) | 2005-10-26 | — | — | EP | disclosed |
| CN-1668741-A | Production of polyketides and other natural products | BIOTICA TECH LTD (GB) | 2005-09-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266896-A1 | PRODUCTION OF POLYKETIDES AND OTHER NATURAL PRODUCTS | FKBP14, FKBP4, FKBP2 | SLC1A2 4426/4885SLC1A1 4237/4885APLNR 1899/4885 |
| US-20080021211-A1 | PRODUCTION OF POLYKETIDES AND OTHER NATURAL PRODUCTS | FKBP14, FKBP4, FKBP2 | SLC1A2 4426/4885SLC1A1 4237/4885APLNR 1899/4885 |
| US-20080287482-A1 | Production of Polyketides and Other Natural Products | FKBP14, FKBP4, FKBP2 | SLC1A2 4426/4885SLC1A1 4237/4885APLNR 1899/4885 |
| US-20080039486-A1 | PRODUCTION OF POLYKETIDES AND OTHER NATURAL PRODUCTS | FKBP14, FKBP4, FKBP2 | SLC1A2 4426/4885SLC1A1 4237/4885APLNR 1899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.