SCHEMBL816717

SCHEMBL816717

Cc1c(C)c(C)c(Br)c(C)c1C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13964572 0.95 LMNA (0.38) LMNA
SCHEMBL1263624 0.95 LMNA (0.35) LMNACYP1A2
SCHEMBL3626193 0.90 LMNA (0.33) LMNA
SCHEMBL30084309 0.90 LMNA (0.33) LMNA
SCHEMBL5095804 0.86 LMNA (0.38) LMNA
SCHEMBL12793959 0.84
SCHEMBL358040 0.84 LMNA (0.42) LMNACYP1A2
SCHEMBL411496 0.82 LMNA (0.30) LMNA
SCHEMBL655518 0.80 CA1 (0.33) LMNA
SCHEMBL14394895 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140005429-A1 Processes for the Preparation of Arylamine Compounds UNIVATION TECHNOLOGIES, LLC (US) 2014-01-02 US claimed
US-8501659-B2 Processes for the preparation of arylamine compounds UNIVATION TECHNOLOGIES, LLC (US) 2013-08-06 US claimed
CN-102209704-A Processes for the preparation of arylamine compounds UNIVATION TECH LLC 2011-10-05 CN claimed
EP-2364290-A2 PROCESSES FOR THE PREPARATION OF ARYLAMINE COMPOUNDS Univation Technologies, LLC (US) 2011-09-14 EP claimed
US-20110207599-A1 Processes for the Preparation of Arylamine Compounds UNIVATION TECHNOLOGIES, LLC (US) 2011-08-25 US claimed
WO-2010053696-A2 PROCESSES FOR THE PREPARATION OF ARYLAMINE COMPOUNDS UNIVATION TECHNOLOGIES, LLC (US) 2010-05-14 WO claimed
EP-4608988-A1 CLOSED-LOOP OPTIMIZATION OF GENERAL REACTION CONDITIONS FOR HETEROARYL SUZUKI-MIYAURA COUPLING THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2025-09-03 EP disclosed
US-20250188106-A1 SUBSTITUTED IMIDAZO[1,5-A]PYRIDINE N-HETEROCYCLIC CARBENE (NHC) LIGANDS, CATALYST COMPLEXES THEREOF, AND METHODS USING SAME RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2025-06-12 US disclosed
WO-2024091573-A1 CLOSED-LOOP OPTIMIZATION OF GENERAL REACTION CONDITIONS FOR HETEROARYL SUZUKI-MIYAURA COUPLING THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2024-05-02 WO disclosed
EP-3708596-B1 NOVEL METALLOCENE CATALYST COMPOUND FOR PRODUCTION OF POLYOLEFIN RESIN OR METHOD OF PREPARING SAME DL CHEMICAL CO LTD (KR) 2024-03-27 EP disclosed
WO-2023243522-A1 METHOD FOR PRODUCING AROMATIC COMPOUND 日本化学工業株式会社 2023-12-21 WO disclosed
US-20230348366-A1 BENZALDEHYDE OXIMES AND METHOD FOR PRODUCING SAME BAYER AKTIENGESELLSCHAFT (DE) 2023-11-02 US disclosed
WO-2023172667-A2 SUBSTITUTED IMIDAZO[1,5-a]PYRIDINE N-HETEROCYCLIC CARBENE (NHC) LIGANDS, CATALYST COMPLEXES THEREOF, AND METHODS USING SAME RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2023-09-14 WO disclosed
CN-1132747-A Bisresorcinyltriazines CIBA GEIGY AG (CH) 1996-10-09 CN disclosed
EP-0728140-A1 NEW STEROIDS WITH RADICAL-ATTRACTING AROMATIC SUBSTITUENTS, PROCESS FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOUNDS CONTAINING THE SAID SUBSTANCES Jenapharm GmbH & Co. KG (DE) 1996-08-28 EP disclosed
US-5504219-A Optically active compounds and intermediates thereof, and process for manufacturing same ASAHI DENKA KOGYO K.K. (JP) 1996-04-02 US disclosed
WO-1995013287-A1 NEW STEROIDS WITH RADICAL-ATTRACTING AROMATIC SUBSTITUENTS, PROCESS FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOUNDS CONTAINING THE SAID SUBSTANCES JENAPHARM GMBH (DE) 1995-05-18 WO disclosed
US-5352845-A Process for manufacture of optically active saturated compounds ASAHI DENKA KOGYO K.K. (JP) 1994-10-04 US disclosed
US-5262552-A Optically active compounds and intermediates thereof, and process for manufacturing same ASAHI DENKA KOGYO K.K. (JP) 1993-11-16 US disclosed
US-4330473-A FLUORAN COLOR-FORMER YAMAMOTO KAGAKU GOSEI KABUSHIKI KAISHA (JP) 1982-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230348366-A1 BENZALDEHYDE OXIMES AND METHOD FOR PRODUCING SAME AOX1, BBOX1, ALDH7A1 LMNA 3281/4885CYP1A2 10/4885
US-20110207599-A1 Processes for the Preparation of Arylamine Compounds NAT1, AADAT, AAAS LMNA 3079/4885CYP1A2 1423/4885
US-20250188106-A1 SUBSTITUTED IMIDAZO[1,5-A]PYRIDINE N-HETEROCYCLIC CARBENE (NHC) LIGANDS, CATALYST COMPLEXES THEREOF, AND METHODS USING SAME NDC1, NUDC, PAICS LMNA 1449/4885CYP1A2 1190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.