SCHEMBL358055

SCHEMBL358055

CCCC[n+]1ccn(C)c1.O=S(=O)([O-])C(F)(F)C(F)C(F)(F)F

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.34
APAF1 O14727 4/20 0.34
KMT2A Q03164 2/20 0.34
NPSR1 Q6W5P4 2/20 0.34
CASP3 P42574 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
ALDH1A1 P00352 4/20 0.33
HTT P42858 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 3/20 0.33
RXFP1 Q9HBX9 2/20 0.33
LMNA P02545 1/20 0.32
MEN1 O00255 1/20 0.31
MITF O75030 1/20 0.31
BLM P54132 1/20 0.31
ACHE P22303 1/20 0.31
PABPC1 P11940 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL534993 0.99 MAPT (0.33) MAPTAPAF1KMT2ANPSR1CASP3
SCHEMBL357139 0.91 ALDH1A1 (0.34) MAPTAPAF1KMT2ANPSR1CASP3
SCHEMBL1736184 0.87 LMNA (0.32) HTTLMNA
SCHEMBL357534 0.87 MAPT (0.32) MAPTAPAF1KMT2ANPSR1CASP3
Trifluoromethanesulfonic Acid SCHEMBL192398 0.87 ACHE (0.40) MAPTNPSR1ALDH1A1HTTSMN1; SMN2
SCHEMBL1736109 0.86 MEN1 (0.34) MAPTAPAF1KMT2AALDH1A1HTT
SCHEMBL358007 0.86 MEN1 (0.34) MAPTAPAF1KMT2AALDH1A1HTT
SCHEMBL1858365 0.86 MEN1 (0.34) MAPTAPAF1KMT2AALDH1A1HTT
SCHEMBL1735956 0.86 MEN1 (0.34) MAPTAPAF1KMT2AALDH1A1HTT
SCHEMBL1736114 0.86 MEN1 (0.34) MAPTAPAF1KMT2AALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8779220-B2 Capture of fluorinated vinyl monomers using ionic liquids E I DU PONT DE NEMOURS AND COMPANY (US) 2014-07-15 US claimed
US-8568608-B2 Vapor compression cycle utilizing ionic liquid as compressor lubricant E I DU PONT DE NEMOURS AND COMPANY (US) 2013-10-29 US claimed
US-20130267668-A1 POLYMERIZATION OF FLUORINATED VINYL MONOMERS IN A BIPHASIC REACTION MEDIUM E I DU PONT DE NEMOURS AND COMPANY (US) 2013-10-10 US claimed
EP-2021276-B1 PROCESS FOR PURIFYING PERFLUORINATED PRODUCTS DU PONT (US) 2013-07-17 EP claimed
US-20130123448-A1 CAPTURE OF FLUORINATED VINYL MONOMERS USING IONIC LIQUIDS E I DU PONT DE NEMOURS AND COMPANY (US) 2013-05-16 US claimed
EP-1954680-B1 IONIC LIQUIDS DU PONT (US) 2012-05-23 EP claimed
EP-2414476-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. du Pont de Nemours and Company (US) 2012-02-08 EP claimed
US-20120011886-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. DU PONT DE NEMOURS AND COMPANY 2012-01-19 US claimed
US-20110195212-A1 Flame Retardant Polycarbonate Compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-08-11 US claimed
WO-2010117836-A1 IONIC COMPOUNDS IN LITHIUM BROMIDE/WATER ABSORPTION CYCLE SYSTEMS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-10-14 WO claimed
EP-1940914-B1 PREPARATION OF POLYTRIMETHYLENE ETHER GLYCOL AND COPOLYMERS THEREOF DU PONT (US) 2009-05-13 EP claimed
US-7528287-B2 Preparation of poly(tetramethylene) glycol E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-05-05 US claimed
WO-2009032961-A2 PROCESSES FOR MAKING DIBUTYL ETHERS FROM 2-BUTANOL E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-03-12 WO claimed
WO-2009032962-A2 PROCESSES FOR MAKING DIBUTYL ETHERS FROM ISOBUTANOL E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-03-12 WO claimed
US-20080221241-A1 Flame Retardant Polycarbonate Compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-09-11 US claimed
US-7238772-B2 Preparation of polytrimethylene ether glycol and copolymers thereof E. I. DU PONT DE NEMOURS AND COMPANY (DE) 2007-07-03 US claimed
US-20070100184-A1 Alkylation of aromatic compounds E. I. DU PONT DE NEMOURS AND COMPANY 2007-05-03 US claimed
US-20070066822-A1 Ionic liquids THE CHEMOURS COMPANY FC, LLC 2007-03-22 US claimed
US-20070066852-A1 Preparation of poly(tetramethylene) glycol THE CHEMOURS COMPANY FC, LLC 2007-03-22 US claimed
US-20070066854-A1 Preparation of polytrimethylene ether glycol and copolymers thereof THE CHEMOURS COMPANY FC, LLC 2007-03-22 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070100184-A1 Alkylation of aromatic compounds TYR, ALK, AHR MAPT 798/4885APAF1 329/4885KMT2A 618/4885
US-20070066854-A1 Preparation of polytrimethylene ether glycol and copolymers thereof PARG, PTGES3, PGD MAPT 2208/4885APAF1 1602/4885KMT2A 3420/4885
US-20130123448-A1 CAPTURE OF FLUORINATED VINYL MONOMERS USING IONIC LIQUIDS VCL, MFAP1, VAV1 MAPT 2067/4885APAF1 2898/4885KMT2A 2538/4885
US-20070066822-A1 Ionic liquids AFF2, AFF1, ZYX MAPT 3942/4885APAF1 3882/4885KMT2A 2696/4885
US-20070066852-A1 Preparation of poly(tetramethylene) glycol PARG, PUF60, TPR MAPT 296/4885APAF1 2585/4885KMT2A 3529/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.