Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.59 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | CSF1R | P07333 | 1/20 | 0.59 |
| ▸ | PIM1 | P11309 | 1/20 | 0.59 |
| ▸ | PHKG2 | P15735 | 1/20 | 0.59 |
| ▸ | MARK3 | P27448 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.59 |
| ▸ | FLT3 | P36888 | 1/20 | 0.59 |
| ▸ | CLK2 | P49760 | 1/20 | 0.59 |
| ▸ | GSK3A | P49840 | 1/20 | 0.59 |
| ▸ | ITK | Q08881 | 1/20 | 0.59 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.59 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.59 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.59 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.59 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.59 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.59 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3589372 | 0.90 | ADORA2A (0.55) | CHEK1MAP4K4LCKCSF1RPIM1 | |
| SCHEMBL3575241 | 0.88 | MAP4K4 (0.72) | CHEK1MAP4K4LCKCSF1RPIM1 | |
| SCHEMBL3580322 | 0.86 | CHEK1 (0.61) | CHEK1MAP4K4LCKCSF1RPIM1 | |
| SCHEMBL3580805 | 0.84 | MAP4K4 (0.79) | CHEK1MAP4K4LCKCSF1RPIM1 | |
| SCHEMBL3575819 | 0.83 | CHEK1 (0.65) | CHEK1MAP4K4LCKCSF1RPIM1 | |
| SCHEMBL6948237 | 0.81 | TSHR (0.50) | LMNAPARP1GAANPC1RAB9A | |
| SCHEMBL6810427 | 0.79 | PKN1 (0.58) | MAP4K4PIM1PHKG2CLK2GSK3A | |
| SCHEMBL3577456 | 0.78 | MAP4K4 (0.59) | CHEK1MAP4K4LCKCSF1RPIM1 | |
| SCHEMBL3585981 | 0.77 | ADORA2A (0.55) | CHEK1MAP4K4LCKCSF1RPIM1 | |
| SCHEMBL3580405 | 0.76 | MMP2 (0.50) | GUSBPARP1POLBGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781596-B1 | Substituted 2-phenylbenzimidazoles, the production thereof and their use | ABBOTT LABORATORIES (US) | 2010-08-24 | — | — | US | disclosed |