Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 5/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 2/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.35 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3581034 | 0.87 | LPAR1 (0.36) | LPAR1LPAR5CA12CA1CA2 | |
| SCHEMBL3580861 | 0.86 | MCL1 (0.38) | PPARGPPARDPPARARCE1SLC2A1 | |
| SCHEMBL3574035 | 0.86 | MEP1B (0.36) | LPAR1LPAR5CA12CA1CA2 | |
| SCHEMBL3581545 | 0.80 | CNR1 (0.40) | LPAR1LPAR5PPARGPPARDPPARA | |
| SCHEMBL1385936 | 0.80 | LPAR1 (0.37) | LPAR1LPAR5CA12CA1CA2 | |
| SCHEMBL3589427 | 0.79 | MCL1 (0.38) | PPARGPPARDPPARARCE1TP53 | |
| SCHEMBL3569982 | 0.77 | LPAR1 (0.41) | LPAR1LPAR5CA12CA1CA2 | |
| SCHEMBL3587845 | 0.77 | LPAR1 (0.42) | LPAR1LPAR5CA12CA1CA2 | |
| SCHEMBL3574614 | 0.77 | HDAC8 (0.39) | LPAR1LPAR5RCE1SLC2A1 | |
| SCHEMBL3581450 | 0.77 | MEP1B (0.41) | LPAR1LPAR5CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |