Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 15/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 15/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 5/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3581537 | 0.87 | PTGER2 (0.42) | HCRTR1HCRTR2PTGER2 | |
| SCHEMBL3570653 | 0.86 | CNR1 (0.39) | — | |
| SCHEMBL3582723 | 0.85 | HCRTR1 (0.37) | HCRTR1HCRTR2PTGER2 | |
| SCHEMBL3576692 | 0.81 | ESRRG (0.37) | — | |
| SCHEMBL3580812 | 0.81 | TRPM8 (0.35) | — | |
| SCHEMBL12521105 | 0.81 | PTGER2 (0.41) | HCRTR1HCRTR2PTGER2 | |
| SCHEMBL12521007 | 0.80 | HCRTR1 (0.41) | HCRTR1HCRTR2PTGER2 | |
| SCHEMBL3576379 | 0.80 | HSP90AA1 (0.46) | — | |
| SCHEMBL3581175 | 0.80 | ESRRG (0.36) | HCRTR1HCRTR2 | |
| SCHEMBL3581186 | 0.79 | CNR1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7678818-B2 | Anthranilamide and 2-amino-heteroarene-carboxamide compounds | HOFFMANN-LA ROCHE INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1984340-B1 | ANTHRANILAMIDE/2-AMINO-HETEROARENE CARBOXAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2012-06-27 | — | — | EP | disclosed |