SCHEMBL4966232

SCHEMBL4966232

CN1[C]=CCc2cc(Cl)ccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.40
NOTUM Q6P988 2/20 0.38
SRD5A1 P18405 5/20 0.38
SRD5A2 P31213 1/20 0.38
LMNA P02545 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
OPRK1 P41145 1/20 0.37
PDE4D Q08499 1/20 0.37
CA12 O43570 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
HSD17B3 P37058 2/20 0.35
AADAT Q8N5Z0 1/20 0.33
SCN9A Q15858 1/20 0.33
DRD2 P14416 1/20 0.33
DRD4 P21917 1/20 0.33
HRH4 Q9H3N8 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3585238 0.77 ALDH1A1 (0.35) NOTUMLMNASMN1; SMN2OPRK1SCN9A
SCHEMBL4962296 0.76 TRIM24 (0.33) DRD2DRD4
SCHEMBL17592884 0.72 POLB (0.43) POLBNOTUMSRD5A1LMNASMN1; SMN2
SCHEMBL1925311 0.66 PKM (0.59) POLBNOTUMSRD5A1SRD5A2LMNA
SCHEMBL8998888 0.66 POLB (0.41) POLBNOTUMSRD5A1SRD5A2LMNA
SCHEMBL31484243 0.64 DRD2 (0.45) POLBLMNASMN1; SMN2OPRK1PDE4D
SCHEMBL28691181 0.64 DRD2 (0.45) POLBLMNASMN1; SMN2OPRK1PDE4D
SCHEMBL11255201 0.64 SRD5A1 (0.59) NOTUMSRD5A1SRD5A2OPRK1PDE4D
SCHEMBL2625777 0.64 NOTUM (0.57) POLBNOTUMSRD5A1LMNASMN1; SMN2
SCHEMBL16817955 0.63 SCN9A (0.46) POLBNOTUMSRD5A1SRD5A2HSD17B3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1896265-A1 OPTICAL INFORMATION-RECORDING MEDIUM AND INFORMATION-RECORDING METHOD Fujifilm Corporation (JP) 2008-03-12 EP disclosed
WO-2007001095-A1 OPTICAL INFORMATION-RECORDING MEDIUM AND INFORMATION-RECORDING METHOD FUJIFILM CORPORATION (JP) 2007-01-04 WO disclosed