Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HEXA | P06865 | 3/20 | 0.40 |
| ▸ | HEXB | P07686 | 3/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10908051 | 0.79 | HTR7 (0.43) | KDM4ELMNAHTR7NPSR1 | |
| SCHEMBL14359201 | 0.74 | KDM4E (0.40) | KDM4ELMNAHTR7USP2NPSR1 | |
| SCHEMBL24939775 | 0.72 | ALDH1A1 (0.57) | KDM4ELMNANPSR1 | |
| SCHEMBL7599227 | 0.72 | MGLL (0.47) | KDM4ELMNAHTR7NPSR1 | |
| SCHEMBL358695 | 0.71 | KDM4E (0.44) | KDM4ELMNAHTR7 | |
| SCHEMBL9656303 | 0.71 | KDM4E (0.44) | KDM4ELMNAHTR7 | |
| SCHEMBL10031631 | 0.71 | LMNA (0.44) | KDM4ELMNAUSP2NPSR1 | |
| SCHEMBL15998794 | 0.71 | KDM4E (0.38) | KDM4ELMNAHTR7 | |
| SCHEMBL1108307 | 0.70 | CA1 (0.41) | HEXAHEXB | |
| SCHEMBL7802057 | 0.70 | MEN1 (0.47) | KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357347-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-11-09 | — | — | US | disclosed |
| WO-2019183577-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357347-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | GIPR, GLP1R, GCGR | KDM4E 3433/4885LMNA 3629/4885HEXA 2205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.