Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28435158 | 0.95 | GAA (0.47) | ROCK1L3MBTL1ALDH1A1GAAMAPT | |
| SCHEMBL2312739 | 0.90 | ROCK1 (0.51) | ROCK1L3MBTL1ALDH1A1GAAMAPT | |
| SCHEMBL3481133 | 0.88 | ALDH1A1 (0.55) | L3MBTL1ALDH1A1GAAMAPTKMT2A | |
| SCHEMBL2061992 | 0.83 | ALDH1A1 (0.51) | L3MBTL1ALDH1A1GAAMAPTKMT2A | |
| SCHEMBL16274458 | 0.81 | ALDH1A1 (0.54) | ROCK1L3MBTL1ALDH1A1GAAMAPT | |
| SCHEMBL31110265 | 0.81 | ROCK1 (0.46) | ROCK1L3MBTL1ALDH1A1GAAMAPT | |
| SCHEMBL29767731 | 0.80 | NLRP3 (0.57) | ROCK1L3MBTL1ALDH1A1MAPTKMT2A | |
| SCHEMBL3585115 | 0.80 | NOTUM (0.56) | L3MBTL1ALDH1A1GAAMAPTKMT2A | |
| SCHEMBL30575716 | 0.80 | NOTUM (0.56) | L3MBTL1ALDH1A1GAAMAPTKMT2A | |
| SCHEMBL2675480 | 0.79 | MAPT (0.48) | ROCK1L3MBTL1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989139-B2 | Azo-metal chelate dye and optical recording medium | MITSUBISHI KAGAKU MEDIA CO., LTD. (JP) | 2011-08-02 | — | — | US | disclosed |
| US-7989139-B2 | Azo-metal chelate dye and optical recording medium | MITSUBISHI KAGAKU MEDIA CO., LTD. (JP) | 2011-08-02 | — | — | US | disclosed |
| EP-1666538-B1 | AZO METAL CHELATE COLORING MATTER AND OPTICAL RECORDING MEDIUM | MITSUBISHI KAGAKU MEDIA CO LTD (JP) | 2011-06-08 | — | — | EP | disclosed |
| US-20100004222-A1 | Amide Derivatives as Ion-Channel Ligands and Pharmaceutical Compositions and Methods of Using the Same | RENOVIS, INC. (US) | 2010-01-07 | — | — | US | disclosed |
| US-20100004222-A1 | Amide Derivatives as Ion-Channel Ligands and Pharmaceutical Compositions and Methods of Using the Same | RENOVIS, INC. (US) | 2010-01-07 | — | — | US | disclosed |
| US-7642036-B2 | Azo-metal chelate dye and optical recording medium | MITSUBISHI KAGAKU MEDIA CO., LTD. (JP) | 2010-01-05 | — | — | US | disclosed |
| US-20090264424-A1 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. | 2009-10-22 | — | — | US | disclosed |
| US-20090264424-A1 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. | 2009-10-22 | — | — | US | disclosed |
| US-20090246687-A1 | AZO-METAL CHELATE DYE AND OPTICAL RECORDING MEDIUM | MITSUBISHI KAGAKU MEDIA CO. LTD. (JP) | 2009-10-01 | — | — | US | disclosed |
| US-20090246687-A1 | AZO-METAL CHELATE DYE AND OPTICAL RECORDING MEDIUM | MITSUBISHI KAGAKU MEDIA CO. LTD. (JP) | 2009-10-01 | — | — | US | disclosed |
| US-20060030618-A1 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. | 2006-02-09 | — | — | US | disclosed |
| US-20050272931-A1 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. | 2005-12-08 | — | — | US | disclosed |
| EP-1463714-A4 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC (US) | 2005-10-19 | — | — | EP | disclosed |
| US-20050227986-A1 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. | 2005-10-13 | — | — | US | disclosed |
| EP-1480954-A1 | VANILLOID RECEPTOR MODULATORS | GLAXO GROUP LIMITED (GB) | 2004-12-01 | — | — | EP | disclosed |
| EP-1463714-A2 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | Amgen Inc. (US) | 2004-10-06 | — | — | EP | disclosed |
| US-20030195201-A1 | Vanilloid receptor ligands and their use in treatments | AMGEN INC. | 2003-10-16 | — | — | US | disclosed |
| WO-2003068749-A1 | VANILLOID RECEPTOR MODULATORS | GLAXO GROUP LIMITED (GB) | 2003-08-21 | — | — | WO | disclosed |
| WO-2003049702-A2 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2003-06-19 | — | — | WO | disclosed |
| US-3948877-A | POLYACRYLONITRILE, ACID MODIFIED POLYESTERS OR POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272931-A1 | Vanilloid receptor ligands and their use in treatments | TRPV1, TRPV2, TRPV3 | ROCK1 1440/4885L3MBTL1 4483/4885ALDH1A1 3238/4885 |
| US-20060030618-A1 | Vanilloid receptor ligands and their use in treatments | TRPV1, TRPV2, TRPV3 | ROCK1 1440/4885L3MBTL1 4483/4885ALDH1A1 3238/4885 |
| US-20100004222-A1 | Amide Derivatives as Ion-Channel Ligands and Pharmaceutical Compositions and Methods of Using the Same | TRPV1, TRPA1, TRPV2 | ROCK1 3959/4885L3MBTL1 3859/4885ALDH1A1 1265/4885 |
| US-20030195201-A1 | Vanilloid receptor ligands and their use in treatments | TRPV1, TRPV2, TRPV3 | ROCK1 1184/4885L3MBTL1 4494/4885ALDH1A1 3105/4885 |
| US-20050227986-A1 | Vanilloid receptor ligands and their use in treatments | TRPV1, TRPV2, TRPV3 | ROCK1 1440/4885L3MBTL1 4483/4885ALDH1A1 3238/4885 |
| US-20090264424-A1 | VANILLOID RECEPTOR LIGANDS AND THEIR USE IN TREATMENTS | TRPV1, TRPV2, TRPV3 | ROCK1 1440/4885L3MBTL1 4483/4885ALDH1A1 3238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.