Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 12/20 | 0.78 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3590575 | 1.00 | SMYD2 (0.78) | SMYD2ADRB1ADRB2DRD2DRD1 | |
| SCHEMBL3607298 | 0.96 | SMYD2 (0.82) | SMYD2ADRB1ADRB2DRD2DRD1 | |
| SCHEMBL3589383 | 0.96 | SMYD2 (0.82) | SMYD2ADRB1ADRB2DRD2DRD1 | |
| Trifluoroacetic Acid SCHEMBL3601614 | 0.95 | SMYD2 (0.73) | SMYD2ADRB1ADRB2DRD2DRD1 | |
| Trifluoroacetic Acid SCHEMBL9107340 | 0.95 | SMYD2 (0.73) | SMYD2ADRB1ADRB2DRD2DRD1 | |
| Trifluoroacetic Acid SCHEMBL3606581 | 0.94 | SMYD2 (0.79) | SMYD2ADRB1ADRB2DRD2DRD1 | |
| Trifluoroacetic Acid SCHEMBL3599481 | 0.92 | SMYD2 (0.91) | SMYD2ADRB1ADRB2DRD2DRD1 | |
| Trifluoroacetic Acid SCHEMBL3605825 | 0.92 | SMYD2 (0.91) | SMYD2ADRB1ADRB2DRD2DRD1 | |
| Trifluoroacetic Acid SCHEMBL3600564 | 0.92 | SMYD2 (0.76) | SMYD2ADRB1ADRB2DRD2DRD1 | |
| Trifluoroacetic Acid SCHEMBL3603568 | 0.92 | SMYD2 (0.76) | SMYD2ADRB1ADRB2DRD2DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120142646-A1 | Novel Compounds 621 | ASTRAZENECA AB (SE) | 2012-06-07 | — | — | US | disclosed |
| US-20100056508-A1 | AMINE DERIVATIVES AND THEIR USE IN BETA-2-ADRENORECEPTOR MEDIATED DISEASES | ASTRAZENECA AB (SE) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120142646-A1 | Novel Compounds 621 | AR, ADRA1D, ADRA1B | SMYD2 3203/4885ADRB1 4/4885ADRB2 18/4885 |
| US-20100056508-A1 | AMINE DERIVATIVES AND THEIR USE IN BETA-2-ADRENORECEPTOR MEDIATED DISEASES | ADRB2, ADRB1, ADRA2A | SMYD2 1024/4885ADRB1 2/4885ADRB2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.