Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC3 | Q13507 | 3/20 | 0.40 |
| ▸ | TRPC7 | Q9HCX4 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | EIF4E | P06730 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CCR2 | P41597 | 3/20 | 0.36 |
| ▸ | CPT1A | P50416 | 2/20 | 0.36 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3586297 | 0.93 | ALDH1A1 (0.43) | TRPC3TRPC7FAAHEIF4EKDM4E | |
| SCHEMBL3580394 | 0.92 | TRPC3 (0.44) | TRPC3TRPC7FAAHKDM4ECPT1A | |
| SCHEMBL3587927 | 0.91 | ALDH1A1 (0.38) | TRPC3TRPC7KDM4EHPGDHSD17B10 | |
| SCHEMBL2297608 | 0.87 | CCR5 (0.43) | KDM4EHPGDHSD17B10ALDH1A1CPT1A | |
| SCHEMBL3591327 | 0.87 | ENPP2 (0.41) | TRPC3TRPC7FAAHKDM4EHPGD | |
| SCHEMBL3634136 | 0.86 | TRPC3 (0.34) | TRPC3TRPC7FAAHKDM4EHPGD | |
| SCHEMBL3593203 | 0.86 | CPT1A (0.44) | KDM4EHPGDHSD17B10ALDH1A1CPT1A | |
| SCHEMBL3587938 | 0.85 | GRIN2B (0.40) | TRPC3TRPC7KDM4EHPGDHSD17B10 | |
| SCHEMBL3591383 | 0.85 | ALDH1A1 (0.37) | TRPC3TRPC7FAAHKDM4EHPGD | |
| SCHEMBL3587524 | 0.84 | MDM2 (0.39) | TRPC3TRPC7KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | MERCK SHARP & DOHME CORP. | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286191-A1 | 2-Arylthiazole Derivatives as CXCR3 Receptor Modulators | CXCR3, CXCR1, CXCR2 | TRPC3 176/4885TRPC7 350/4885FAAH 2194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.