SCHEMBL358812

SCHEMBL358812

O=S(=O)(O)C(F)(F)C(F)(F)C(F)F

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TSHR P16473 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL3975885 0.97 ALDH1A1 (0.35) ALDH1A1L3MBTL1TSHRTDP1KDM4E
Water SCHEMBL9499164 0.97 ALDH1A1 (0.35) ALDH1A1L3MBTL1TSHRTDP1KDM4E
Nitrogen SCHEMBL8667242 0.95 ALDH1A1 (0.33) ALDH1A1L3MBTL1TSHRTDP1KDM4E
SCHEMBL11290143 0.84 KDM4E (0.40) ALDH1A1L3MBTL1TSHRTDP1KDM4E
SCHEMBL1827433 0.82 KDM4E (0.39) ALDH1A1L3MBTL1TSHRTDP1KDM4E
SCHEMBL11902989 0.82 KDM4E (0.39) ALDH1A1L3MBTL1TSHRTDP1KDM4E
SCHEMBL1829776 0.80 TSHR (0.38) ALDH1A1L3MBTL1TSHRTDP1KDM4E
SCHEMBL5484308 0.80 TSHR (0.38) ALDH1A1L3MBTL1TSHRTDP1KDM4E
SCHEMBL1824726 0.80 TSHR (0.38) ALDH1A1L3MBTL1TSHRTDP1KDM4E
SCHEMBL5485456 0.80 TSHR (0.38) ALDH1A1L3MBTL1TSHRTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024175523-A1 ACCEPTOR-SUBSTITUTED EUV PAGS WITH HIGH ELECTRON AFFINITY MERCK PATENT GMBH (DE) 2024-08-29 WO claimed
CN-117897430-A Process for preparing polytrimethylene ether glycol and polytrimethylene ether glycol prepared using the process SK化学株式会社 2024-04-16 CN claimed
US-20220410134-A1 ALKYLATION CATALYST COMPOSITION AND RELATED METHODS UNIVERSITY OF KANSAS 2022-12-29 US claimed
EP-2326744-B1 METAL COMPOSITIONS AND METHODS OF MAKING SAME PRYOG LLC (US) 2022-06-01 EP claimed
WO-2021097200-A1 ALKYLATION CATALYST COMPOSITION AND RELATED METHODS UNIVERSITY OF KANSAS (US) 2021-05-20 WO claimed
US-10071943-B2 Copper catalyzed [18F]fluorination of iodonium salts THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2018-09-11 US claimed
US-20170036980-A1 COPPER CATALYZED [18F]FLUORINATION OF IODONIUM SALTS THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2017-02-09 US claimed
WO-2015157597-A1 COPPER CATALYZED [18F]FLUORINATION OF IODONIUM SALTS THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2015-10-15 WO claimed
EP-2021276-B1 PROCESS FOR PURIFYING PERFLUORINATED PRODUCTS DU PONT (US) 2013-07-17 EP claimed
US-20100143995-A1 Process for Fermentive Preparation of Alcohols and Recovery of Product E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-10 US claimed
US-5347038-A Starting material for quinacridone pigments, pollution control, from succinic acid diester and aniline HOECHST AKTIENGESELLSCHAFT (DE) 1994-09-13 US claimed
US-5264633-A Process for the preparation of 1,4-bis(4-hydroxybenzoyl)benzene HOECHST AKTIENGESELLSCHAFT (DE) 1993-11-23 US claimed
EP-0558511-A1 METHOD OF PREPARING 2,5-DI(PHENYLAMINO)TEREPHTHALIC ACID AND ITS DIALKYL ESTERS AS HIGH-PURITY PRODUCTS. HOECHST AG (DE) 1993-09-08 EP claimed
EP-0394985-B1 PROCESS FOR PREPARING NITRO BENZOIC ACID ALKYL ESTERS HOECHST AKTIENGESELLSCHAFT (DE) 1993-04-07 EP claimed
WO-1992015549-A1 UNSATURATED POLYMERS AND RADIATION-SENSITIVE MIXTURE MADE THEREFROM HOECHST AKTIENGESELLSCHAFT (DE) 1992-09-17 WO claimed
EP-0498847-A1 PROCESS FOR PRODUCING 1,4-bis-(4-HYDROXYBENZOYL)BENZOL. HOECHST AG (DE) 1992-08-19 EP claimed
WO-1992009558-A1 METHOD OF PREPARING 2,5-DI(PHENYLAMINO)TEREPHTHALIC ACID AND ITS DIALKYL ESTERS AS HIGH-PURITY PRODUCTS HOECHST AKTIENGESELLSCHAFT (DE) 1992-06-11 WO claimed
US-5087725-A PROCESS FOR THE PREPARATION OF ALKYL NITROBENZOATES HOECHST AKTIENGESELLSCHAFT (DE) 1992-02-11 US claimed
WO-1991006524-A1 PROCESS FOR PRODUCING 1,4-bis-(4-HYDROXYBENZOYL)BENZOL HOECHST AKTIENGESELLSCHAFT (DE) 1991-05-16 WO claimed
EP-0394985-A1 Process for preparing nitro benzoic acid alkyl esters HOECHST AKTIENGESELLSCHAFT (DE) 1990-10-31 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170036980-A1 COPPER CATALYZED [18F]FLUORINATION OF IODONIUM SALTS SOD1, TPO, FLI1 ALDH1A1 177/4885L3MBTL1 3080/4885TSHR 418/4885
US-10071943-B2 Copper catalyzed [18F]fluorination of iodonium salts SOD1, TPO, FLI1 ALDH1A1 177/4885L3MBTL1 3080/4885TSHR 418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.