⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9806073 | 0.82 | DGAT1 (0.39) | — | |
| SCHEMBL132957 | 0.82 | — | — | |
| SCHEMBL23869987 | 0.80 | — | — | |
| SCHEMBL1240770 | 0.78 | DGAT1 (0.36) | — | |
| SCHEMBL28776282 | 0.78 | ALDH1A1 (0.39) | — | |
| Potassium Fluoride SCHEMBL27832151 | 0.78 | DGAT1 (0.36) | — | |
| Fluoride Ion SCHEMBL176967 | 0.78 | DGAT1 (0.36) | — | |
| SCHEMBL3650176 | 0.75 | ALDH1A1 (0.32) | — | |
| SCHEMBL2580230 | 0.75 | DGAT1 (0.42) | — | |
| SCHEMBL3841392 | 0.75 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081937-B1 | TRIAZOLOPYRIDAZINE PROTEIN KINASE MODULATORS | SGX PHARMACEUTICALS INC (US) | 2012-09-12 | — | — | EP | disclosed |
| US-8071581-B2 | Triazolopyridazine protein kinase modulators | SGX PHARMACEUTICALS, INC. (US) | 2011-12-06 | — | — | US | disclosed |
| US-20100120739-A1 | TRIAZOLOPYRIDAZINE PROTEIN KINASE MODULATORS | SGX PHARMACEUTICALS, INC. | 2010-05-13 | — | — | US | disclosed |
| EP-2081937-A2 | TRIAZOLOPYRIDAZINE PROTEIN KINASE MODULATORS | SGX Pharmaceuticals, Inc. (US) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008051805-A2 | TRIAZOLO-PYRIDAZINE PROTEIN KINASE MODULATORS | SGX PHARMACEUTICALS, INC. (US) | 2008-05-02 | — | — | WO | disclosed |
| US-7247757-B2 | Method of producing a fluorine-containing vinyl ether compound | FUJIFILM CORPORATION (JP) | 2007-07-24 | — | — | US | disclosed |
| US-7247757-B2 | Method of producing a fluorine-containing vinyl ether compound | FUJIFILM CORPORATION (JP) | 2007-07-24 | — | — | US | disclosed |
| US-7247757-B2 | Method of producing a fluorine-containing vinyl ether compound | FUJIFILM CORPORATION (JP) | 2007-07-24 | — | — | US | disclosed |
| US-20060074264-A1 | Method of producing a flourine-containing vinyl ether compound | FUJI PHOTO FILM CO., LTD. | 2006-04-06 | — | — | US | disclosed |
| US-5880162-A | INSECTICIDES FOR SOIL BORNE INSECT PESTS | BRITISH TECHNOLOGY GROUP, LTD. (GB) | 1999-03-09 | — | — | US | disclosed |
| EP-0227369-B1 | INSECTICIDAL ALKENES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-04-18 | — | — | EP | disclosed |
| US-4904677-A | Certain phenoxy- or benzyl substituted pyridylmethyloxy-alkenes having insecticidal properties | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-02-27 | — | — | US | disclosed |
| EP-0346107-A2 | Arylfluoroalkenamides and their use as pesticides | ROUSSEL UCLAF (FR) | 1989-12-13 | — | — | EP | disclosed |
| US-4812483-A | PESTICIDES, MITICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-03-14 | — | — | US | disclosed |
| EP-0227369-A1 | Insecticidal alkenes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-07-01 | — | — | EP | disclosed |
| EP-0014437-B1 | NOVEL 1-ARYL-2-ACYLAMIDO-3-FLUORO-1-PROPANOLS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1983-02-23 | — | — | EP | disclosed |
| US-4361557-A | 1-Aryl-2-acylamido-3-fluoro-1-propanol acylates, methods for their use as anti-bacterial agents and compositions useful therefor | SCHERING CORPORATION (US) | 1982-11-30 | — | — | US | disclosed |
| US-4311857-A | 1-Aryl-2-acylamido-3-fluoro-1-propanol acylates, methods for their manufacture and intermediates useful therein, methods for their use as antibacterial agents and compositions useful therefor | SCHERING CORPORATION (US) | 1982-01-19 | — | — | US | disclosed |
| US-4235892-A | AROMATIC ANTIBIOTICS | Schering Corporation, Patent Dept. (US) | 1980-11-25 | — | — | US | disclosed |
| EP-0014437-A2 | Novel 1-aryl-2-acylamido-3-fluoro-1-propanols, their preparation and pharmaceutical compositions containing them | SCHERING CORPORATION (US) | 1980-08-20 | — | — | EP | disclosed |