Potassium Fluoride

Potassium Fluoride

SCHEMBL27832151

COC(=O)C(F)(F)Cl.F[K]

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.36
ALDH1A1 P00352 3/20 0.35
KCNN4 O15554 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL132957 0.95
Fluoride Ion SCHEMBL176967 0.90 DGAT1 (0.36) DGAT1ALDH1A1KCNN4L3MBTL1MAPT
SCHEMBL30957003 0.80 PKM (0.40) ALDH1A1L3MBTL1MAPT
SCHEMBL3592898 0.78
SCHEMBL9806073 0.78 DGAT1 (0.39) DGAT1ALDH1A1KCNN4L3MBTL1MAPT
SCHEMBL23869987 0.76
SCHEMBL1240770 0.74 DGAT1 (0.36) DGAT1ALDH1A1KCNN4L3MBTL1MAPT
SCHEMBL28776282 0.74 ALDH1A1 (0.39) DGAT1ALDH1A1KCNN4L3MBTL1MAPT
SCHEMBL18398859 0.73
SCHEMBL8165907 0.72 DGAT1 (0.39) DGAT1ALDH1A1KCNN4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102171192-A Indazole compounds ASAHI KASEI PHARMA CORP 2011-08-31 CN disclosed
CN-102089303-A Nitrogenated heterocyclic compound ASAHI KASEI PHARMA CORP 2011-06-08 CN disclosed