SCHEMBL132957

SCHEMBL132957

COC(=O)C(F)(F)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium Fluoride SCHEMBL27832151 0.95 DGAT1 (0.36)
Fluoride Ion SCHEMBL176967 0.95 DGAT1 (0.36)
SCHEMBL30957003 0.84 PKM (0.40)
SCHEMBL9806073 0.82 DGAT1 (0.39)
SCHEMBL3592898 0.82
SCHEMBL23869987 0.80
SCHEMBL1240770 0.78 DGAT1 (0.36)
SCHEMBL28776282 0.78 ALDH1A1 (0.39)
SCHEMBL18398859 0.78
SCHEMBL8165907 0.77 DGAT1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120149553-A Non-corrosive electrolyte solvent, electrolyte and battery 上海交通大学 2025-06-13 CN claimed
CN-115872889-A Method for preparing o-trifluoromethylaniline compound 沈阳中化农药化工研发有限公司 2023-03-31 CN claimed
CN-114671817-B 5-CF 3 -1,2, 3-triazole compound and preparation method and application thereof 四川大学华西医院 2022-11-18 CN claimed
CN-114671862-B 18F-labeled radioactive tracer and preparation method thereof 四川大学华西医院 2022-11-11 CN claimed
CN-114671817-A 5-CF3-1,2, 3-triazole compound and preparation method and application thereof 四川大学华西医院 2022-06-28 CN claimed
CN-114249765-A Fluorine-containing pentavalent phosphorus compound and preparation method thereof 西安交通大学 2022-03-29 CN claimed
CN-111620811-B Novel liquid crystal raw material, chiral catalyst ligand compound and synthesis method thereof 河北松辰医药科技有限公司 2021-11-05 CN claimed
CN-109867645-B Synthetic method of 2, 2-difluoro-2, 3-dihydro-substituted benzofuran compound 中国医学科学院药物研究所 2021-09-14 CN claimed
CN-111620811-A Novel liquid crystal raw material, chiral catalyst ligand compound and synthesis method thereof 河北松辰医药科技有限公司 2020-09-04 CN claimed
US-10483466-B2 P-doping cross-linking of organic hole transporters SIEMENS AKTIENGESELLSCHAFT (DE) 2019-11-19 US claimed
EP-1670742-A1 PROCESS FOR THE PREPARATION OF ROFLUMILAST Ranbaxy Laboratories Limited (IN) 2006-06-21 EP claimed
WO-2005026095-A1 PROCESS FOR THE PREPARATION OF ROFLUMILAST RANBAXY LABORATORIES LIMITED (IN) 2005-03-24 WO claimed
CN-1174970-C Method of preparing 3-haloalkyl-1H-pyrazoles G��D��ɪ����˾ 2004-11-10 CN claimed
EP-0828717-B1 METHOD OF PREPARING 3-HALOALKYL-1H-PYRAZOLES SEARLE & CO (US) 2002-09-04 EP claimed
US-5910597-A Process for preparing 3-haloalkyl-1H-pyrazoles G.D. SEARLE & CO. (US) 1999-06-08 US claimed
US-5892053-A Process for preparing 3-haloalkyl-1H-pyrazoles G. D. SEARLE & CO. (US) 1999-04-06 US claimed
CN-1190960-A Method of preparing 3-haloalkyl-1H-pyrazoles SEARLE & CO (US) 1998-08-19 CN claimed
US-5731477-A Method for synthesis of aryl difluoromethyl ethers SMITHKLINE BEECHAM CORPORATION (US) 1998-03-24 US claimed
EP-0828717-A1 METHOD OF PREPARING 3-HALOALKYL-1H-PYRAZOLES G.D. SEARLE &amp; CO. (US) 1998-03-18 EP claimed
WO-1996037476-A1 METHOD OF PREPARING 3-HALOALKYL-1H-PYRAZOLES G.D. SEARLE & CO. (US) 1996-11-28 WO claimed