SCHEMBL359304

SCHEMBL359304

COCc1c(F)c(F)c(COC(=O)C2C(C=O)C2(C)C)c(F)c1F

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.55
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
LMNA P02545 2/20 0.39
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
ADRA2A P08913 1/20 0.35
CNR1 P21554 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2580946 1.00 TDP1 (0.55) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL2579133 1.00 TDP1 (0.55) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL7105787 0.93 TDP1 (0.58) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL1539210 0.89 TDP1 (0.53) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL7918010 0.89 TDP1 (0.68) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL472943 0.89 TDP1 (0.68) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL24119147 0.88 TDP1 (0.54) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL117637 0.88 TDP1 (0.54) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL134831 0.88 TDP1 (0.54) TDP1MEN1KMT2ALMNACYP1A2
SCHEMBL7592007 0.88 TDP1 (0.54) TDP1MEN1KMT2ALMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2412702-B1 METHOD FOR PRODUCING CYCLOPROPANECARBOXYLIC ACID ESTER SUMITOMO CHEMICAL CO (JP) 2014-12-03 EP disclosed
EP-1970369-B1 METHOD FOR PRODUCING PURIFIED FORMYLCYCLOPROPANE COMPOUND AND INTERMEDIATE OF SUCH FORMYLCYCLOPROPANE COMPOUND SUMITOMO CHEMICAL CO (JP) 2013-09-25 EP disclosed
US-8461370-B2 Process for producing 3-(2-cyano-1-propenyl)-2,2- dimethylcyclopropanecarboxylic acid or salt thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-06-11 US disclosed
US-8263797-B2 Method for producing cyclopropane carboxylic acid compound and intermediate therefor SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-09-11 US disclosed
US-8168816-B2 Method for producing purified formylcyclopropane compound and intermediate of such formylcyclopropane compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-01 US disclosed
EP-1535895-B1 PROCESS FOR PRODUCTION OF FORMYLCYCLOPROPANECARBOXYLIC ESTERS SUMITOMO CHEMICAL CO (JP) 2012-04-25 EP disclosed
US-20120029227-A1 METHOD FOR PRODUCING CYCLOPROPANECARBOXYLIC ACID ESTER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-02 US disclosed
EP-2412702-A1 METHOD FOR PRODUCING CYCLOPROPANECARBOXYLIC ACID ESTER Sumitomo Chemical Company, Limited (JP) 2012-02-01 EP disclosed
US-20120016150-A1 Process for Producing 3-(2-Cyano-1-propenyl)-2,2- Dimethylcyclopropanecarboxylic Acid or Salt Thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-19 US disclosed
EP-1609776-B1 PROCESS FOR PRODUCTION OF CARBONYL COMPOUNDS SUMITOMO CHEMICAL CO (JP) 2011-03-02 EP disclosed
EP-1463706-A1 PROCESS FOR PRODUCTION OF 3,3-DIMETHYL-2-FORMYLCYCLOPROPANECARBOXYLIC ACID DERIVATIVES Sumitomo Chemical Company, Limited (JP) 2004-10-06 EP disclosed
EP-1462441-A1 CYCLOPROPANECARBOXYLIC ACID ESTERS AND PEST CONTROLLERS CONTAINING THE SAME Sumitomo Chemical Company, Limited (JP) 2004-09-29 EP disclosed
US-20040152592-A1 Process for producing carbonyl or hydroxy compound SUMITOMO CHEMICAL COMPANY, LIMTED 2004-08-05 US disclosed
US-6703528-B2 CATALYTIC OXIDATION OF OLEFIN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-03-09 US disclosed
US-20030195119-A1 2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl 2-(2-cyanopropenyl)-3,3-dimethylcyclopropanecarboxylate; pesticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-10-16 US disclosed
WO-2003066559-A1 PROCESS FOR PRODUCTION OF ALDEHYDES AND KETONES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-08-14 WO disclosed
WO-2003066566-A1 PROCESS FOR THE PRODUCTION OF TRANS-3,3-DIMETHYL-2-FORMLCYCLOPROPANE CARBOXYLIC ACID ESTERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-08-14 WO disclosed
WO-2003059861-A1 PROCESS FOR PRODUCTION OF 3,3-DIMETHYL-2-FORMYLCYCLOPROPANECARBOXYLIC ACID DERIVATIVES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-24 WO disclosed
EP-1188735-A1 Process for producing carbonyl or hydroxy compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-20 EP disclosed
EP-1120393-A1 A process for producing 3,3-dimethyl-2-formylcyclopropane-carboxylic acid ester SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-08-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120029227-A1 METHOD FOR PRODUCING CYCLOPROPANECARBOXYLIC ACID ESTER PCCA, COASY, GRHPR TDP1 4158/4885MEN1 3565/4885KMT2A 3385/4885
US-20120016150-A1 Process for Producing 3-(2-Cyano-1-propenyl)-2,2- Dimethylcyclopropanecarboxylic Acid or Salt Thereof CPS1, PCCA, PKD1 TDP1 3167/4885MEN1 1087/4885KMT2A 1950/4885
US-20030195119-A1 2,3,5,6-tetrafluoro-4-(methoxymethyl)benzyl 2-(2-cyanopropenyl)-3,3-dimethylcyclopropanecarboxylate; pesticides DDT, CASP3, CASP2 TDP1 1436/4885MEN1 1823/4885KMT2A 2012/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.