Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | PEPD | P12955 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3586977 | 0.79 | CYP3A4 (0.34) | L3MBTL1 | |
| SCHEMBL3601322 | 0.73 | BRD4 (0.37) | — | |
| SCHEMBL16846630 | 0.73 | KLKB1 (0.30) | — | |
| SCHEMBL3590039 | 0.72 | ALDH1A1 (0.41) | L3MBTL1 | |
| SCHEMBL3587636 | 0.66 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL3597233 | 0.65 | SMN1; SMN2 (0.37) | — | |
| Acetic Acid SCHEMBL28552652 | 0.63 | PIK3CD (0.39) | — | |
| SCHEMBL19838911 | 0.62 | CYP19A1 (0.39) | CYP19A1CYP2D6PEPDGAAXPNPEP1 | |
| SCHEMBL24960898 | 0.61 | SMN1; SMN2 (0.45) | CYP2D6GAA | |
| SCHEMBL12125010 | 0.61 | CYP2D6 (0.39) | L3MBTL1CYP2D6PEPD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728028-B2 | Substituted imidazoline compounds | GRUENENTHAL GMBH (DE) | 2010-06-01 | — | — | US | disclosed |
| US-20090048323-A1 | SUBSTITUTED IMIDAZOLINE COMPOUNDS | GRUENENTHAL GMBH (DE) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048323-A1 | SUBSTITUTED IMIDAZOLINE COMPOUNDS | ITCH, OPRK1, ALDH1A1 | CYP19A1 1547/4885L3MBTL1 3010/4885CYP2D6 85/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.