SCHEMBL359368

SCHEMBL359368

Cc1c(F)c(F)c(CO)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 4/20 0.33
TAS1R1 Q7RTX1 4/20 0.33
TAS1R2 Q8TE23 4/20 0.33
GCGR P47871 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1808733 0.95 TAS1R3 (0.31) TAS1R3TAS1R1TAS1R2
SCHEMBL29843172 0.89 TAS1R3 (0.31) TAS1R3TAS1R1TAS1R2
SCHEMBL19688010 0.89 TAS1R3 (0.31) TAS1R3TAS1R1TAS1R2
Diethylamine SCHEMBL9785736 0.86 TP53 (0.35) TAS1R3TAS1R1TAS1R2
SCHEMBL359564 0.86 GCGR (0.30) GCGR
SCHEMBL522934 0.84 POLB (0.33)
SCHEMBL27411309 0.83 IMPDH2 (0.31)
SCHEMBL19478237 0.83 IMPDH2 (0.35)
SCHEMBL19478251 0.83 DRD4 (0.34)
SCHEMBL19688017 0.82 GCGR (0.31) GCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117776870-A Synthesis method of 4-methyl-2, 3,5, 6-tetrafluorobenzyl alcohol 江苏优士化学有限公司 2024-03-29 CN claimed
CN-115215726-A Synthesis method of 4-methyl-2, 3,5, 6-tetrafluorobenzyl alcohol 江苏优士化学有限公司 2022-10-21 CN claimed
CN-114106304-A Low-temperature curing weather-resistant polyester resin, low-temperature curing weather-resistant powder coating and preparation method 安徽神剑新材料股份有限公司 2022-03-01 CN claimed
CN-102964218-B Process for preparing 4-methyl-2, 3, 5, 6-tetrafluorobenzyl alcohol ZHEJIANG ZHONGXIN CHEMICALS CO LTD 2015-05-20 CN claimed
EP-2778152-A1 METHOD FOR PRODUCING 4-HYDROXYMETHYL-2,3,5,6-TETRAFLUOROTOLUENE Sumitomo Chemical Company Limited (JP) 2014-09-17 EP claimed
EP-2471766-B1 Process for producing 4-methyl-2,3,5,6-tetrafluorobenzyl alcohol SUMITOMO CHEMICAL CO (JP) 2013-09-04 EP claimed
EP-1915331-B1 PRODUCTION PROCESS OF NUCLEUS-HALOGENATED METHYLBENZYL ALCOHOL SHOWA DENKO KK (JP) 2013-07-10 EP claimed
EP-2123624-B1 METHOD FOR PRODUCING 4-METHYL-2,3,5,6-TETRAFLUOROBENZYL ALCOHOL SUMITOMO CHEMICAL CO (JP) 2013-04-17 EP claimed
EP-2471766-A1 Process for producing 4-methyl-2,3,5,6-tetrafluorobenzyl alcohol Sumitomo Chemical Company, Limited (JP) 2012-07-04 EP claimed
US-20120130118-A1 METHODS FOR PRODUCING AND USING A TETRAFLUOROTOLUENE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-05-24 US claimed
EP-1322584-A2 PROCESS FOR PRODUCING FLUORINATED METHYL-BENZYL ALCOHOL Showa Denko K.K. (JP) 2003-07-02 EP claimed
EP-1303474-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE PYRETHROID INSECTICIDES Syngenta Limited (GB) 2003-04-23 EP claimed
WO-2002034706-A1 PREPARATION OF 4-METHYL-2, 3, 5, 6-TETRAFLUOROBENZYL ALCOHOL SYNGENTA LIMITED (GB) 2002-05-02 WO claimed
WO-2002034707-A1 PREPARATION OF 4-METHYL-2,3,5,6-TETRAFLUOROBENZYL ALCOHOL SYNGENTA LIMITED (GB) 2002-05-02 WO claimed
WO-2002026678-A2 PROCESS FOR PRODUCING FLUORINATED METHYL-BENZYL ALCOHOL SHOWA DENKO K.K. (JP) 2002-04-04 WO claimed
WO-2002006202-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE PYRETHROID INSECTICIDES SYNGENTA LIMITED (GB) 2002-01-24 WO claimed
EP-0152174-B1 SELECTIVE HYDROGENATION OF BENZENE DI- AND TRI-METHANOL COMPOUNDS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1992-03-18 EP claimed
US-4661488-A Pyrimidine substituted-2,2-dimethylcyclopropane carboxylates useful for combating insect and acarine pests at a locus IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-04-28 US claimed
EP-0162538-A2 Cyclopropane derivates IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-11-27 EP claimed
US-4429153-A INSECTICIDES, MITICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-01-31 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120130118-A1 METHODS FOR PRODUCING AND USING A TETRAFLUOROTOLUENE COMPOUND ADH1C, ADH1A, CYP2E1 TAS1R3 980/4885TAS1R1 639/4885TAS1R2 909/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.