SCHEMBL522934

SCHEMBL522934

OCc1c(F)c(F)c(CO)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
DRD4 P21917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL536295 0.96 POLB (0.32) POLBSMN1; SMN2DRD4
SCHEMBL522960 0.93 POLB (0.32) POLB
SCHEMBL24834493 0.89 POLB (0.31) POLB
SCHEMBL522840 0.88 SMN1; SMN2 (0.30) SMN1; SMN2DRD4
SCHEMBL21322546 0.87 DRD4 (0.38) POLBDRD4
SCHEMBL16026415 0.87 POLB (0.30) POLB
SCHEMBL31549436 0.87 POLB (0.30) POLB
SCHEMBL6441426 0.84
SCHEMBL9175838 0.84 SMN1; SMN2 (0.31) SMN1; SMN2
SCHEMBL2524562 0.84 DRD4 (0.31) DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 383 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120192507-A Preparation method and application of synergistically modified aqueous polyurethane emulsion 山东海化集团有限公司 2025-06-24 CN claimed
CN-120192497-A Preparation method and application of epoxy modified castor oil based fluorine-containing aqueous polyurethane emulsion 山东海化集团有限公司 2025-06-24 CN claimed
WO-2025128627-A1 FLUORINATED THERMOPLASTIC POLYURETHANE ABIOMED, INC. (US) 2025-06-19 WO claimed
US-20250188216-A1 FLUORINATED THERMOPLASTIC POLYURETHANE ABIOMED, INC. (US) 2025-06-12 US claimed
CN-120118366-A MLCC release film base film and preparation method thereof 扬州博恒新能源材料科技有限公司 2025-06-10 CN claimed
CN-119281632-B Rare earth metal element doped silicon steel sheet and preparation method thereof 江苏甬金金属科技有限公司 2025-06-10 CN claimed
CN-120040393-A Method for synthesizing furfuryl acetate compounds by carbonyl synthesis of furfuryl alcohol and derivatives 中国科学院兰州化学物理研究所 2025-05-27 CN claimed
CN-116786160-B Preparation of fluorine-containing ionic liquid catalyst and high-efficiency CO thereof2Application in transformation 浙江理工大学嵊州创新研究院有限公司 2025-05-23 CN claimed
CN-119842183-A Composite material for coating-free one-step forming photovoltaic bracket bridge and application thereof 江西龙正科技发展有限公司 2025-04-18 CN claimed
CN-116586113-B Method for preparing dual-function heterogeneous catalyst and application thereof in catalyzing CO2Use in cycloaddition conversion with epoxides 浙江理工大学 2025-04-11 CN claimed
US-20040010167-A1 Process for producing fluorinated methyl-benzyl alcohol SHOWA DENKO K.K. (JP) 2004-01-15 US claimed
EP-1110938-B1 Method for producing 4-methoxymethyl-2,3,5,6-tetrafluorobenzenemethanol SUMITOMO CHEMICAL CO (JP) 2003-11-05 EP claimed
US-6624336-B1 Acetalization of tetrafluorobenzonitriles using alcohols, in the presence of mineral acids and metal catalysts to form chemical intermediates for nontoxic insecticides SHOWA DENKO K.K. (JP) 2003-09-23 US claimed
US-20030171626-A1 Production method for benzenedimethanol compound SHOWA DENKO K.K. (JP) 2003-09-11 US claimed
EP-1339666-A1 PREPARATION OF 4-METHYL-2,3,5,6-TETRAFLUOROBENZYL ALCOHOL Syngenta Limited (GB) 2003-09-03 EP claimed
WO-2002034706-A1 PREPARATION OF 4-METHYL-2, 3, 5, 6-TETRAFLUOROBENZYL ALCOHOL SYNGENTA LIMITED (GB) 2002-05-02 WO claimed
EP-1182184-A1 PROCESS FOR PRODUCING TETRAFLUORO BENZENEMETHANOLS Showa Denko K K (JP) 2002-02-27 EP claimed
US-6339176-B2 BY REACTING 2,3,5,6-TETRAFLUORO-1,4-BENZENEDIMETHANOL WITH AN INORGANIC BASE IN WATER, ADDING DIMETHYL SULFATE AND A WATER IMMISCIBLE ORGANIC SOLVENT OF EITHER HYDROCARBONS OR ETHERS TO THE REACTION MIXTURE; INSECTICIDES; MONOMETHYLATION SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2002-01-15 US claimed
EP-1110938-A1 Method for producing 4-methoxymethyl-2,3,5,6-tetrafluorobenzenemethanol SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-06-27 EP claimed
US-20010003138-A1 Method for producing 4-methoxymethy1-2,3,5,6-tetrafluorobenzenemethanol SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-06-07 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010003138-A1 Method for producing 4-methoxymethy1-2,3,5,6-tetrafluorobenzenemethanol MSMO1, TDO2, PMM2 POLB 1625/4885SMN1; SMN2 2877/4885DRD4 921/4885
US-20040010167-A1 Process for producing fluorinated methyl-benzyl alcohol ADH1C, ADH5, ADH1A POLB 779/4885SMN1; SMN2 3506/4885DRD4 73/4885
US-20030171626-A1 Production method for benzenedimethanol compound NNMT, HNMT, GNMT POLB 2875/4885SMN1; SMN2 2648/4885DRD4 118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.