SCHEMBL3593973

SCHEMBL3593973

O=C(O)NCC1CCN(CCc2ccc(Cl)cc2Cl)CC1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 1/20 0.51
ARG2 P78540 1/20 0.51
EPHX2 P34913 3/20 0.49
F10 P00742 8/20 0.48
CACNA1I Q9P0X4 2/20 0.47
MAOA P21397 1/20 0.47
MAOB P27338 1/20 0.47
KCNH2 Q12809 1/20 0.47
SIGMAR1 Q99720 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3594120 0.81 MAPT (0.55) CACNA1IKCNH2SIGMAR1L3MBTL1
SCHEMBL3594726 0.77 HIF1A (0.46) CACNA1IL3MBTL1
SCHEMBL3598760 0.77 TP53 (0.44) CACNA1IKCNH2
SCHEMBL3593611 0.76 USP30 (0.50) F10CACNA1IKCNH2L3MBTL1
SCHEMBL3937038 0.76 CHRM4 (0.52) ARG1ARG2EPHX2MAOAMAOB
SCHEMBL3593975 0.76 CCR5 (0.60) ARG1ARG2MAOAMAOBSIGMAR1
SCHEMBL23123778 0.76 CCR3 (0.61) SIGMAR1
SCHEMBL3593316 0.76 CCR2 (0.67) CACNA1IKCNH2SIGMAR1
SCHEMBL2975028 0.76 ARG1 (0.44) ARG1ARG2EPHX2MAOAMAOB
SCHEMBL3592322 0.75 POLB (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1720550-B1 DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS SANOFI AVENTIS (FR) 2009-04-15 EP claimed
US-20100279998-A1 PIPERIDINYLALKYLCARBAMATE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THE THERAPEUTIC USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS SANOFI-AVENTIS (FR) 2010-11-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100279998-A1 PIPERIDINYLALKYLCARBAMATE DERIVATIVES, METHODS FOR THEIR PREPARATION AND THE THERAPEUTIC USE THEREOF AS FATTY ACID AMIDO HYDROLASE ENZYME INHIBITORS FAAH, FAAH2, CNR2 ARG1 3164/4885ARG2 3119/4885EPHX2 65/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.