Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 4/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.35 |
| ▸ | HTR3B | O95264 | 3/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1608105 | 0.83 | HRH3 (0.33) | KDM4EGAAMAPTALDH1A1GFER | |
| SCHEMBL1607692 | 0.78 | LMNA (0.41) | KDM4EMAPTALDH1A1KMT2AMAPK1 | |
| SCHEMBL1606819 | 0.78 | ADRB1 (0.41) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL1907933 | 0.69 | ACHE (0.40) | ADRA2CMAPTKMT2AESR2DRD2 | |
| SCHEMBL7672750 | 0.68 | MC4R (0.48) | KDM4EALDH1A1CHKAMC4R | |
| SCHEMBL1852924 | 0.65 | ADRA2C (0.44) | ADRA2CKDM4EGAAMAPTPTK2B | |
| SCHEMBL3340768 | 0.65 | MEN1 (0.33) | KDM4EGAAMAPTALDH1A1KMT2A | |
| SCHEMBL28420185 | 0.64 | MAPT (0.37) | ADRA2CKDM4EGAAMAPTPTK2B | |
| SCHEMBL18228156 | 0.64 | HRH4 (0.40) | ADRA2CKDM4EGAAMAPTPTK2B | |
| SCHEMBL933508 | 0.63 | HTR3A (0.42) | ADRA2CKDM4EALDH1A1HTR3AHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029636-A1 | Lck inhibitors | NOVARTIS AG (CH) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029636-A1 | Lck inhibitors | LCK, ZAP70, FYN | ADRA2C 3317/4885KDM4E 557/4885GAA 3549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.