Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 10/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382940 | 1.00 | APP (0.48) | APPCA2MAPK14MIFLMNA | |
| SCHEMBL251926 | 1.00 | APP (0.48) | APPCA2MAPK14MIFLMNA | |
| SCHEMBL1133835 | 0.86 | ALDH1A1 (0.43) | APPCA2MAPK14LMNAMAPT | |
| SCHEMBL1133834 | 0.86 | ALDH1A1 (0.43) | APPCA2MAPK14LMNAMAPT | |
| SCHEMBL24060753 | 0.86 | CA2 (0.44) | APPCA2MAPK14LMNAHTT | |
| SCHEMBL25158926 | 0.85 | APP (0.56) | APPCA2MAPK14LMNAHTT | |
| SCHEMBL7165644 | 0.84 | ALDH1A1 (0.45) | APPCA2MAPK14LMNAMAPT | |
| SCHEMBL12673084 | 0.84 | ALDH1A1 (0.46) | CA2MAPK14ALDH1A1TP53TSHR | |
| SCHEMBL3297902 | 0.83 | CA2 (0.42) | APPCA2MAPK14HSD17B10MAPT | |
| SCHEMBL6267008 | 0.82 | PKM (0.51) | APPCA2MAPK14LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117940405-A | Novel compounds exhibiting therapeutic effects on inflammatory diseases as p38 MAP kinase inhibitors | 普瑞泽治疗公司 | 2024-04-26 | — | — | CN | disclosed |
| US-8741834-B2 | Dipeptoid prodrugs and the use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-06-03 | — | — | US | disclosed |
| US-8741834-B2 | Dipeptoid prodrugs and the use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-06-03 | — | — | US | disclosed |
| US-8691850-B2 | Substituted phenylaminothiazoles and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-04-08 | — | — | US | disclosed |
| US-8691850-B2 | Substituted phenylaminothiazoles and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-04-08 | — | — | US | disclosed |
| US-20110294719-A1 | DIPEPTOID PRODRUGS AND THE USE THEREOF | Bayer Schering Pharma | 2011-12-01 | — | — | US | disclosed |
| US-20110294719-A1 | DIPEPTOID PRODRUGS AND THE USE THEREOF | Bayer Schering Pharma | 2011-12-01 | — | — | US | disclosed |
| US-20110237629-A1 | AMINO ACID ESTER PRODRUGS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-09-29 | — | — | US | disclosed |
| US-20110237629-A1 | AMINO ACID ESTER PRODRUGS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2011-09-29 | — | — | US | disclosed |
| WO-2010072314-A1 | DIPEPTOID PRODRUGS AND THE USE THEREOF | BAYER SCHERING PHARMA AG (DE) | 2010-07-01 | — | — | WO | disclosed |
| EP-1812430-A1 | SUBSTITUTED PHENYLAMINOTHIAZOLES AND USE THEREOF | Bayer HealthCare AG (DE) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006065659-A2 | INSECTICIDAL BIS(SUBSTITUTED PHENYL)-1-{[4-(SATURATED HETEROCYCLYL-SUBSTITUTED)PHENYLMETHYL]-(4-PIPERIDYL)}METHANE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2006-06-22 | — | — | WO | disclosed |
| WO-2006027142-A1 | SUBSTITUTED PHENYLAMINOTHIAZOLES AND USE THEREOF | BAYER HEALTHCARE AG (DE) | 2006-03-16 | — | — | WO | disclosed |
| US-5474988-A | Analgesics, antiinflammatory agents | KALI-CHEMIE PHARMA GMBH (DE) | 1995-12-12 | — | — | US | disclosed |
| US-5395910-A | Photostable polymers | AKZO NOBEL N.V. (NL) | 1995-03-07 | — | — | US | disclosed |
| EP-0350113-B1 | Liquid crystalline polyesters | AKZO NOBEL NV (NL) | 1995-01-25 | — | — | EP | disclosed |
| EP-0550105-A2 | Liquid-crystalline polyurethanes, compositions of said liquid-crystalline polyurethanes, and a device for optical data storage comprising a liquid-crystalline polyurethane | Akzo Nobel N.V. (NL) | 1993-07-07 | — | — | EP | disclosed |
| US-4959448-A | Optical waveguides | AKZO N.V. (NL) | 1990-09-25 | — | — | US | disclosed |
| US-4900727-A | ANTIALLERGENS, ANALGESICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-02-13 | — | — | US | disclosed |
| EP-0350113-A1 | Liquid crystalline polyesters | Akzo Nobel N.V. (NL) | 1990-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294719-A1 | DIPEPTOID PRODRUGS AND THE USE THEREOF | DPP4, DPP3, DNPEP | APP 911/4885CA2 1601/4885MAPK14 1195/4885 |
| US-20110237629-A1 | AMINO ACID ESTER PRODRUGS AND THE USE THEREOF | DNPEP, AADAT, DAO | APP 566/4885CA2 1422/4885MAPK14 673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.