Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 3/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1133835 | 0.92 | ALDH1A1 (0.43) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL1133834 | 0.92 | ALDH1A1 (0.43) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL382940 | 0.84 | APP (0.48) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL251926 | 0.84 | APP (0.48) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL3598217 | 0.84 | APP (0.48) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL6270189 | 0.84 | L3MBTL1 (0.40) | MAPTMAPK14HTR1AADRA1DADRA1B | |
| SCHEMBL27452158 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL16358110 | 0.81 | TMEM97 (0.37) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL27390202 | 0.80 | ALDH1A1 (0.49) | ALDH1A1HPGDMAPTSMN1; SMN2LMNA | |
| SCHEMBL16013097 | 0.80 | MAPK14 (0.40) | ALDH1A1HPGDMAPTSMN1; SMN2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6548652-B2 | Microarray for use in the detection and counting of particle in sample; for use as medical and forensics tools | EPOCH BIOSCIENCES, INC. | 2003-04-15 | — | — | US | disclosed |
| US-20020137045-A1 | Attachment of oligonucleotides to solid supports through schiff base type linkages for capture and detection of nucleic acids | ELITECHGROUP, INC. | 2002-09-26 | — | — | US | disclosed |
| US-6441159-B1 | PHOSPHORAMIDITE REAGENT WITH PROTECTED AROMATIC ALDEHYDE USED TO INTRODUCE ALDEHYDE GROUP INTO OLIGONUCLEOTIDE DURING STANDARD AUTOMATED SYNTHESIS SO IT CAN REACT WITH NUCLEOPHILIC NH2 (SEMICARBAZIDE) GROUPS LINKED TO THE SOLID SUPPORT | EPOCH BIOSCIENCES, INC. | 2002-08-27 | — | — | US | disclosed |
| US-20020081591-A1 | Attachment of oligonucleotides to solid supports through schiff base type linkages for capture and detection of nucleic acids | EPOCH BIOSCIENCES, INC. | 2002-06-27 | — | — | US | disclosed |
| EP-1200628-A2 | ATTACHMENT OF OLIGONUCLEOTIDES TO SOLID SUPPORTS THROUGH SCHIFF BASE TYPE LINKAGES FOR CAPTURE AND DETECTION OF NUCLEIC ACIDS | Epoch Biosciences, Inc. (US) | 2002-05-02 | — | — | EP | disclosed |
| US-6339147-B1 | OLIGONUCLEOTIDES JOINED TO SOLID SUPPORTS | EPOCH BIOSCIENCES, INC. | 2002-01-15 | — | — | US | disclosed |
| WO-2001009385-A2 | ATTACHMENT OF OLIGONUCLEOTIDES TO SOLID SUPPORTS THROUGH SCHIFF BASE TYPE LINKAGES FOR CAPTURE AND DETECTION OF NUCLEIC ACIDS | EPOCH BIOSCIENCES, INC. (US) | 2001-02-08 | — | — | WO | disclosed |
| US-5395910-A | Photostable polymers | AKZO NOBEL N.V. (NL) | 1995-03-07 | — | — | US | disclosed |
| EP-0550105-A2 | Liquid-crystalline polyurethanes, compositions of said liquid-crystalline polyurethanes, and a device for optical data storage comprising a liquid-crystalline polyurethane | Akzo Nobel N.V. (NL) | 1993-07-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020081591-A1 | Attachment of oligonucleotides to solid supports through schiff base type linkages for capture and detection of nucleic acids | RNGTT, SSU72, NSUN2 | ALDH1A1 913/4885HPGD 4292/4885MAPT 4159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.