Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3605612 | 0.91 | CNR1 (0.43) | P2RX7DPP4SMN1; SMN2DPP8CNR1 | |
| SCHEMBL3593028 | 0.86 | ALDH1A1 (0.44) | DPP4DPP8ALDH1A1HPGDGAA | |
| SCHEMBL3601694 | 0.86 | BCL2L2 (0.45) | P2RX7DPP4SMN1; SMN2DPP8ALDH1A1 | |
| SCHEMBL3091146 | 0.83 | DPP4 (0.46) | CYP11B1CYP11B2P2RX7DPP4SMN1; SMN2 | |
| SCHEMBL3600972 | 0.83 | DPP4 (0.41) | CYP11B1CYP11B2DPP4SMN1; SMN2DPP8 | |
| SCHEMBL3597763 | 0.82 | MARS1 (0.42) | P2RX7DPP4PIK3CDDPP8ALDH1A1 | |
| SCHEMBL3599723 | 0.82 | CNR1 (0.42) | DPP4DPP8CNR1TP53HSD11B1 | |
| SCHEMBL3597074 | 0.81 | CNR1 (0.44) | P2RX7DPP4SMN1; SMN2DPP8CNR1 | |
| SCHEMBL3594733 | 0.79 | CXCR2 (0.44) | DPP4SMN1; SMN2DPP8ALDH1A1HPGD | |
| SCHEMBL3592478 | 0.78 | P2RX7 (0.44) | P2RX7DPP4DPP8IDO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |