Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | ACP1 | P24666 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3602324 | 0.91 | CYP11B1 (0.41) | CNR1P2RX7DPP4DPP8SMN1; SMN2 | |
| SCHEMBL3599723 | 0.89 | CNR1 (0.42) | CNR1DPP4DPP8CYP3A4SLC6A2 | |
| SCHEMBL3593028 | 0.88 | ALDH1A1 (0.44) | CNR1DPP4DPP8CYP2C19CYP3A4 | |
| SCHEMBL3601694 | 0.88 | BCL2L2 (0.45) | P2RX7DPP4DPP8CYP2D6TSHR | |
| SCHEMBL3597763 | 0.84 | MARS1 (0.42) | P2RX7DPP4DPP8ADRA1DCYP2D6 | |
| SCHEMBL3597074 | 0.83 | CNR1 (0.44) | CNR1P2RX7DPP4DPP8CYP2D6 | |
| SCHEMBL3600972 | 0.82 | DPP4 (0.41) | CNR1DPP4DPP8TSHRCYP2C19 | |
| SCHEMBL3084580 | 0.81 | DPP4 (0.49) | CNR1PHF8P2RX7DPP4DPP8 | |
| SCHEMBL3594733 | 0.81 | CXCR2 (0.44) | CNR1DPP4DPP8ADRA1DCYP2D6 | |
| SCHEMBL3592478 | 0.80 | P2RX7 (0.44) | P2RX7DPP4DPP8ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728146-B2 | Enzyme inhibitors | PROBIODRUG AG (DE) | 2010-06-01 | — | — | US | claimed |