Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3605760 | 0.89 | MAPK14 (0.66) | MAPK14TRPM8ALDH1A1LMNAHPGD | |
| SCHEMBL3592626 | 0.84 | CSNK1D (0.47) | MAPK14TRPM8JAK3KDM4ECSNK1D | |
| SCHEMBL3606513 | 0.80 | LMNA (0.45) | MAPK14ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL3613513 | 0.78 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL12497225 | 0.76 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL3592492 | 0.74 | STK17B (0.43) | MAPK14ALDH1A1LMNAHPGDKDM4E | |
| SCHEMBL3598647 | 0.72 | PIN1 (0.44) | ALDH1A1LMNAHPGDKDM4EHSD17B10 | |
| SCHEMBL5639017 | 0.72 | NPC1 (0.49) | ALDH1A1HPGDKDM4EMAPTRAB9A | |
| SCHEMBL6018669 | 0.71 | MAPK14 (0.65) | MAPK14TRPM8ALDH1A1HPGDKDM4E | |
| SCHEMBL10109873 | 0.71 | TRPM8 (0.54) | MAPK14TRPM8ALDH1A1LMNAJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835476-B2 | Synthesis of novel antimicrobials | WU FAN (CA) | 2014-09-16 | — | — | US | disclosed |
| US-20100076028-A1 | Design and Synthesis of Novel Antimicrobials | WU FAN | 2010-03-25 | — | — | US | disclosed |
| WO-2006092059-A1 | DESIGN AND SYNTHESIS OF NOVEL ANTIMICROBIALS | WU FAN (CA) | 2006-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076028-A1 | Design and Synthesis of Novel Antimicrobials | MLX, LPXN, TPX2 | MAPK14 3384/4885TRPM8 2375/4885ALDH1A1 4295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.