Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69204 | 0.83 | — | — | |
| 4-Imidazolecarboxylic Acid SCHEMBL13733596 | 0.77 | KDM4E (0.45) | MAPK1 | |
| Biphenyl SCHEMBL27647991 | 0.73 | AXL (0.48) | MAPK1 | |
| Trifluoroacetic Acid SCHEMBL30271697 | 0.73 | MAPK1 (0.40) | MAPK1 | |
| SCHEMBL5572213 | 0.72 | GABRP (0.34) | — | |
| SCHEMBL13733597 | 0.70 | MAPK1 (0.37) | MAPK1 | |
| Acetone SCHEMBL29183514 | 0.68 | GABRP (0.34) | — | |
| Acetone SCHEMBL28453050 | 0.68 | — | — | |
| SCHEMBL3189182 | 0.68 | KDM4E (0.40) | MAPK1 | |
| Ethaneperoxoic Acid SCHEMBL31288599 | 0.67 | GABRP (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7728028-B2 | Substituted imidazoline compounds | GRUENENTHAL GMBH (DE) | 2010-06-01 | — | — | US | disclosed |
| US-20090048323-A1 | SUBSTITUTED IMIDAZOLINE COMPOUNDS | GRUENENTHAL GMBH (DE) | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048323-A1 | SUBSTITUTED IMIDAZOLINE COMPOUNDS | ITCH, OPRK1, ALDH1A1 | MAPK1 1120/4885PLAT 3843/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.