Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | BAD | Q92934 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3606815 | 0.82 | MAPT (0.46) | L3MBTL1TDP1HSP90AB1SMN1; SMN2LMNA | |
| SCHEMBL15155184 | 0.80 | L3MBTL1 (0.64) | L3MBTL1TDP1SMN1; SMN2LMNAPKM | |
| SCHEMBL15155096 | 0.80 | LMNA (0.57) | L3MBTL1TDP1SMN1; SMN2LMNAEGLN1 | |
| SCHEMBL15155139 | 0.80 | ALDH1A1 (0.55) | L3MBTL1SMN1; SMN2LMNAPKMKMT2A | |
| SCHEMBL3606843 | 0.80 | MAPT (0.63) | L3MBTL1HSP90AB1LMNAPKMKMT2A | |
| SCHEMBL553830 | 0.77 | L3MBTL1 (0.62) | L3MBTL1TDP1HPGDSALKBH2POLB | |
| SCHEMBL15155001 | 0.77 | CREBBP (0.57) | L3MBTL1SMN1; SMN2EGLN1HPGDSALKBH2 | |
| SCHEMBL28760613 | 0.77 | EPHX2 (0.51) | L3MBTL1TDP1PKMGAAKMT2A | |
| SCHEMBL18586270 | 0.76 | HSP90AB1 (0.47) | L3MBTL1HSP90AB1SMN1; SMN2LMNAPKM | |
| SCHEMBL14692522 | 0.76 | L3MBTL1 (0.48) | L3MBTL1TDP1LMNAPKMEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041696-A1 | Compounds | SMITHKLINE BEECHAM CORPORATION | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041696-A1 | Compounds | CYP11B2, SCD, CYP3A5 | L3MBTL1 4424/4885TDP1 1525/4885HSP90AB1 3802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.