Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CDC25B | P30305 | 3/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CDC25C | P30307 | 1/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3096725 | 0.83 | ALDH1A1 (0.56) | MAPTLMNAALDH1A1HPGDKMT2A | |
| SCHEMBL3602663 | 0.82 | L3MBTL1 (0.47) | LMNAKMT2ASMN1; SMN2HSP90AB1L3MBTL1 | |
| SCHEMBL30739039 | 0.80 | GRM2 (0.40) | MAPTLMNAALDH1A1HPGDKMT2A | |
| SCHEMBL4767723 | 0.80 | KDM4E (0.49) | ALDH1A1KMT2AGRM2KDM4ETDP1 | |
| SCHEMBL553848 | 0.80 | ALDH1A1 (0.60) | LMNAALDH1A1MAPK1SMN1; SMN2GRM2 | |
| SCHEMBL2819485 | 0.79 | KLKB1 (0.55) | MAPTLMNAALDH1A1HPGDKMT2A | |
| SCHEMBL30736841 | 0.78 | CRHBP (0.44) | MAPTLMNAALDH1A1HPGDKMT2A | |
| SCHEMBL2822906 | 0.77 | ALDH1A1 (0.53) | LMNAALDH1A1SMN1; SMN2GRM2L3MBTL1 | |
| SCHEMBL16150243 | 0.77 | MEN1 (0.42) | MAPTLMNAALDH1A1KMT2ATP53 | |
| SCHEMBL20541407 | 0.76 | GRM2 (0.47) | LMNAALDH1A1HPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041696-A1 | Compounds | SMITHKLINE BEECHAM CORPORATION | 2010-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100041696-A1 | Compounds | CYP11B2, SCD, CYP3A5 | MAPT 3377/4885LMNA 1551/4885ALDH1A1 430/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.