Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diphenylether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.62 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.62 |
| ▸ | BAX | Q07812 | 1/20 | 0.62 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.52 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.52 |
| ▸ | FEN1 | P39748 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylether SCHEMBL1965337 | 1.00 | LTA4H (0.75) | LTA4HTSHRPARP10NR1H2BAX | |
| Diphenylether SCHEMBL5606885 | 1.00 | LTA4H (0.75) | LTA4HTSHRPARP10NR1H2BAX | |
| Diphenylether SCHEMBL7033901 | 0.89 | LTA4H (0.60) | LTA4HTSHRPARP10NR1H2BAX | |
| Diphenylether SCHEMBL9846088 | 0.89 | LTA4H (0.60) | LTA4HTSHRPARP10NR1H2BAX | |
| Diphenylether SCHEMBL10618785 | 0.88 | PARP10 (0.71) | LTA4HTSHRPARP10NR1H2BAX | |
| Diphenylether SCHEMBL29175285 | 0.88 | LTA4H (0.67) | LTA4HTSHRPARP10NR1H2BAX | |
| Diphenylether SCHEMBL1830446 | 0.88 | LTA4H (0.67) | LTA4HTSHRPARP10NR1H2BAX | |
| Diphenylether SCHEMBL7637273 | 0.88 | LTA4H (0.67) | LTA4HTSHRPARP10NR1H2BAX | |
| Diphenylether SCHEMBL28412058 | 0.88 | LTA4H (0.67) | LTA4HTSHRPARP10NR1H2BAX | |
| Diphenylether SCHEMBL8165466 | 0.88 | PARP10 (0.71) | LTA4HTSHRPARP10NR1H2BAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 364 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3559095-B1 | PLASTIC FILMS FOR ID DOCUMENTS WITH IMPROVED LASER ENGRAVING AND IMPROVED CHEMICAL RESISTANCE | COVESTRO DEUTSCHLAND AG (DE) | 2021-08-04 | — | — | EP | claimed |
| EP-3559095-A1 | PLASTIC FILMS FOR ID DOCUMENTS HAVING IMPROVED PROPERTIES FOR LASER ENGRAVING AND IMPROVED CHEMICAL RESISTANCE | Covestro Deutschland AG (DE) | 2019-10-30 | — | — | EP | claimed |
| EP-3502164-A1 | POLYAMIDE MOULDING MATERIAL | EMS-Patent AG (CH) | 2019-06-26 | — | — | EP | claimed |
| EP-3444114-A1 | REINFORCED POLYAMIDE MOULDING COMPOUNDS WITH LOW HAZE AND MOULDS THEREFROM | EMS-Patent AG (CH) | 2019-02-20 | — | — | EP | claimed |
| EP-3444113-A1 | REINFORCED POLYAMIDE MOULDING COMPOUNDS WITH LOW HAZE AND MOULDS THEREFROM | EMS-Patent AG (CH) | 2019-02-20 | — | — | EP | claimed |
| EP-3444112-A1 | REINFORCED POLYAMIDE MOULDING COMPOUNDS WITH LOW HAZE AND MOULDS THEREFROM | EMS-Patent AG (CH) | 2019-02-20 | — | — | EP | claimed |
| WO-2018114836-A1 | PLASTIC FILMS FOR ID DOCUMENTS HAVING IMPROVED PROPERTIES FOR LASER ENGRAVING AND IMPROVED CHEMICAL RESISTANCE | COVESTRO DEUTSCHLAND AG (DE) | 2018-06-28 | — | — | WO | claimed |
| EP-2789647-B1 | Thermo-shrinkable polyester film | KOLON INC (KR) | 2018-06-13 | — | — | EP | claimed |
| EP-2554576-B1 | HEAT-SHRINKABLE POLYESTER-BASED FILM AND HEAT-SHRINKABLE POLYESTER-BASED LABEL | KOLON INC (KR) | 2018-03-21 | — | — | EP | claimed |
| EP-2220148-B1 | THERMO-SHRINKABLE POLYESTER FILM | KOLON INC (KR) | 2018-02-07 | — | — | EP | claimed |
| EP-1769015-B1 | SULFONATED AROMATIC COPOLYESTERS CONTAINING HYDROXYALKANOIC ACID GROUPS AND SHAPED ARTICLES PRODUCED THEREFROM | DU PONT (US) | 2010-08-25 | — | — | EP | claimed |
| EP-1110988-B1 | CATALYST FOR POLYESTER PRODUCTION AND PROCESS FOR PRODUCING POLYESTER WITH THE SAME | TEIJIN LTD (JP) | 2005-04-27 | — | — | EP | claimed |
| EP-0856025-B1 | CHOLESTERIC PHASE-FORMING POLYMERS AND THEIR USE | CELANESE VENTURES GMBH (DE) | 2003-01-15 | — | — | EP | claimed |
| EP-0459395-B1 | Positive photo-sensitive resin composition | SUMITOMO BAKELITE CO (JP) | 1999-08-18 | — | — | EP | claimed |
| EP-0504058-B1 | Process for preparing polyether-amide block polymers | ATOCHEM ELF SA (FR) | 1998-05-13 | — | — | EP | claimed |
| EP-0701996-A1 | Process for the separation of aminodiphenyl from diphenylamine | BAYER AG (DE) | 1996-03-20 | — | — | EP | claimed |
| EP-0408042-B1 | Heat-sealable laminated polyester film | DIAFOIL HOECHST CO LTD (JP) | 1995-09-20 | — | — | EP | claimed |
| EP-0213286-B1 | PROCESS FOR THE FABRICATION OF AROMATIC POLYAMIDES | HÜLS AKTIENGESELLSCHAFT (DE) | 1989-08-23 | — | — | EP | claimed |
| EP-0213286-A2 | Process for the fabrication of aromatic polyamides | HÜLS AKTIENGESELLSCHAFT (DE) | 1987-03-11 | — | — | EP | claimed |
| EP-0037403-B1 | HEAT ACTIVATABLE ADHESIVE WITH IMPROVED TEMPERATURE RESISTANCE | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1984-10-17 | — | — | EP | claimed |