SCHEMBL3602994

SCHEMBL3602994

O=C(Nc1nc(C(=O)O)cs1)c1ccc(Cl)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.59
MEN1 O00255 3/20 0.59
HTT P42858 3/20 0.59
KMT2A Q03164 3/20 0.59
LMNA P02545 2/20 0.59
F2 P00734 1/20 0.59
ADORA3 P0DMS8 2/20 0.57
L3MBTL1 Q9Y468 1/20 0.56
SCD O00767 1/20 0.53
P4HTM Q9NXG6 1/20 0.52
RAB9A P51151 6/20 0.52
NPC1 O15118 5/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
KDM4E B2RXH2 2/20 0.51
TLR7 Q9NYK1 1/20 0.51
NPSR1 Q6W5P4 2/20 0.50
RXFP1 Q9HBX9 2/20 0.50
PLCG2 P16885 1/20 0.50
ALDH1A1 P00352 1/20 0.50
HPGD P15428 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3592974 0.88 MAPT (0.59) MAPTMEN1HTTKMT2ALMNA
SCHEMBL3603304 0.86 NPC1 (0.68) MAPTMEN1HTTKMT2ALMNA
SCHEMBL3604622 0.85 KDM4E (0.59) MAPTMEN1HTTKMT2ALMNA
SCHEMBL4887357 0.84 SMN1; SMN2 (0.55) MAPTLMNAADORA3L3MBTL1RAB9A
SCHEMBL6985089 0.82 KDM4E (0.69) MAPTMEN1HTTKMT2ALMNA
SCHEMBL23742077 0.81 CA1 (0.55) MAPTMEN1HTTKMT2ALMNA
SCHEMBL3607875 0.81 L3MBTL1 (0.55) MAPTMEN1KMT2AL3MBTL1RAB9A
SCHEMBL3600361 0.81 PDE5A (0.62) MAPTMEN1KMT2ALMNAL3MBTL1
SCHEMBL3608921 0.80 SMN1; SMN2 (0.78) MAPTMEN1KMT2ALMNAL3MBTL1
SCHEMBL7503742 0.79 EGFR (0.50) MAPTLMNAL3MBTL1SCDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7799738-B2 Insecticidal 2-acylaminothiazole-4-carboxamides BAYER CROPSCIENCE AG (DE) 2010-09-21 US disclosed
US-20080300136-A1 Insecticidal 2-Acylaminothiazole-4-Carboxamides BAYER CROPSCIENCE AG (DE) 2008-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080300136-A1 Insecticidal 2-Acylaminothiazole-4-Carboxamides AADAC, HDHD5, HRH4 MAPT 4652/4885MEN1 3967/4885HTT 2081/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.