Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.57 |
| ▸ | RXRA | P19793 | 2/20 | 0.55 |
| ▸ | RXRB | P28702 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 3/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | PTPRC | P08575 | 1/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3604393 | 1.00 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1POLBRAB9AALDH1A1 | |
| SCHEMBL22386732 | 0.89 | SMN1; SMN2 (0.69) | SMN1; SMN2NPC1POLBRAB9AALDH1A1 | |
| SCHEMBL2633871 | 0.85 | CES2 (0.59) | RAB9AALDH1A1MAPTHPGDPARP10 | |
| SCHEMBL13826563 | 0.85 | SMN1; SMN2 (0.68) | SMN1; SMN2NPC1POLBRAB9AALDH1A1 | |
| SCHEMBL11075081 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1POLBRAB9AALDH1A1 | |
| SCHEMBL3613095 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1POLBRAB9AALDH1A1 | |
| SCHEMBL3613091 | 0.82 | SMN1; SMN2 (0.59) | SMN1; SMN2NPC1POLBRAB9AALDH1A1 | |
| SCHEMBL933577 | 0.81 | MAOB (0.76) | SMN1; SMN2NPC1POLBRAB9AALDH1A1 | |
| SCHEMBL28335896 | 0.81 | RAB9A (1.00) | SMN1; SMN2NPC1POLBRAB9AALDH1A1 | |
| SCHEMBL1186510 | 0.81 | RAB9A (1.00) | SMN1; SMN2NPC1POLBRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100168156-A1 | Novel Benzoxathiine Derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-07-01 | — | — | US | disclosed |
| EP-1944301-A1 | NOVEL BENZOXATHIIN DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-07-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168156-A1 | Novel Benzoxathiine Derivative | XDH, GPR119, BRIX1 | SMN1; SMN2 3660/4885NPC1 3375/4885POLB 4459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.