SCHEMBL360539

SCHEMBL360539

O=S(=O)(O)c1cc(CBr)ccc1CBr

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.35
RECQL P46063 1/20 0.35
ESR2 Q92731 1/20 0.35
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
HIF1A Q16665 2/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
EGFR P00533 1/20 0.30
PTPN1 P18031 1/20 0.30
CDC25A P30304 1/20 0.30
CDC25B P30305 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6429457 0.81 ALDH1A1 (0.40) POLBLMNAHPGDHSD17B10
SCHEMBL361093 0.80 ESR2 (0.36) POLBRECQLESR2CES2CES1
SCHEMBL20854261 0.79 ALDH1A1 (0.39) POLBLMNAHPGDHSD17B10
SCHEMBL18289517 0.78 MEN1 (0.35) POLBRECQLESR2
SCHEMBL259655 0.74 EGFR (0.42) POLBRECQLESR2CYP4F2CYP4A11
SCHEMBL2622530 0.74 ALDH1A1 (0.47) POLBRECQLESR2HIF1ALMNA
Hydrochloric Acid SCHEMBL27763840 0.74 CYP4F2 (0.40) RECQLCES2CES1CYP4F2CYP4A11
SCHEMBL7662070 0.74 NT5E (0.47) POLBHIF1AHPGD
SCHEMBL819786 0.74 MYC (0.44)
SCHEMBL20719962 0.73 CA1 (0.39) POLBRECQLESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1023309-B1 HIGH SURFACE DENSITY COVALENT IMMOBILIZATION OF OLIGONUCLEOTIDE MONOLAYERS SENSORCHEM INTERNAT CORP (CA) 2003-09-03 EP claimed
US-20240319424-A1 PATTERNED COATABLE THIN-FILM POLARIZER BASED ON LYOTROPIC LIQUID CRYSTAL LIGHT POLYMERS HOLDING (KY) 2024-09-26 US disclosed
US-12072520-B2 Linear polarizers and methods of forming a linear polarizer LIGHT POLYMERS HOLDING (KY) 2024-08-27 US disclosed
US-11998615-B2 Functionalized nanoparticles and their use in treating bacterial infections THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2024-06-04 US disclosed
US-20240148882-A1 METHODS OF TREATING AN OCULAR DISEASE OR DISORDER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-05-09 US disclosed
US-20230145287-A1 LINEAR POLARIZERS AND METHODS OF FORMING A LINEAR POLARIZER LIGHT POLYMERS HOLDING (KY) 2023-05-11 US disclosed
US-20230145287-A1 LINEAR POLARIZERS AND METHODS OF FORMING A LINEAR POLARIZER LIGHT POLYMERS HOLDING (KY) 2023-05-11 US disclosed
US-20230145287-A1 LINEAR POLARIZERS AND METHODS OF FORMING A LINEAR POLARIZER LIGHT POLYMERS HOLDING (KY) 2023-05-11 US disclosed
US-11370914-B2 Methods of forming polymeric polarizers from lyotropic liquid crystals and polymeric polarizers formed thereby LIGHT POLYMERS HOLDING (KY) 2022-06-28 US disclosed
US-10765759-B2 Methods of treating an ocular disease or disorder THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-09-08 US disclosed
US-20040126838-A1 Follicle stimulating hormone: remodeling and glycoconjugation of FSH NEOSE TECHNOLOGIES, INC. 2004-07-01 US disclosed
US-20040115168-A1 Interferon beta: remodeling and glycoconjugation of interferon beta NEOSE TECHNOLOGIES, INC. 2004-06-17 US disclosed
US-20040082026-A1 Interferon alpha: remodeling and glycoconjugation of interferon alpha NEOSE TECHNOLOGIES, INC. 2004-04-29 US disclosed
US-20040077836-A1 Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF NEOSE TECHNOLOGIES, INC. 2004-04-22 US disclosed
US-20040063911-A1 Protein remodeling methods and proteins/peptides produced by the methods NEOSE TECHNOLOGIES, INC. 2004-04-01 US disclosed
US-20040043446-A1 Alpha galalctosidase a: remodeling and glycoconjugation of alpha galactosidase A NEOSE TECHNOLOGIES, INC. 2004-03-04 US disclosed
EP-1023309-B1 HIGH SURFACE DENSITY COVALENT IMMOBILIZATION OF OLIGONUCLEOTIDE MONOLAYERS SENSORCHEM INTERNAT CORP (CA) 2003-09-03 EP disclosed
US-6169194-B1 COMPOUND USED AS COMPONENT OF NOVEL SILANIZATION PROCEDURE WHICH ALLOWS VERY HIGH DENSITY MONOLAYER OF EXPOSED THIOL GROUPS TO BE PLACED ON VARIETY OF HYDROXYLIC SURFACES IN REPRODUCIBLE MANNER SENSORCHEM INTERNATIONAL CORPORATION (CA) 2001-01-02 US disclosed
US-6159695-A High surface density covalent immobilization of oligonucleotide monolayers SENSORCHEM INTERNATIONAL CORPORATION (CA) 2000-12-12 US disclosed
US-5965106-A ADMINISTERING TARGETING MOIETY COUPLED TO AFFINITY COMPONENT, WHEREIN TARGETING MOIETY HAS AFFINITY FOR BINDING SITES IN TARGET AREA, AND BINDING PARTNER TO AFFINITY COMPONENT COUPLED TO FUNCTIONAL MOIETY TO LOCALIZE FUNCTIONAL MOIETY IN TARGET PERIMMUNE HOLDINGS, INC. (US) 1999-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040077836-A1 Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF CSF3R, CSF1R, GMFG POLB 3982/4885RECQL 4761/4885ESR2 2832/4885
US-20040082026-A1 Interferon alpha: remodeling and glycoconjugation of interferon alpha IFNG, IFNAR1, IRF3 POLB 843/4885RECQL 3537/4885ESR2 2658/4885
US-20040063911-A1 Protein remodeling methods and proteins/peptides produced by the methods PTMS, ANPEP, SMURF1 POLB 2938/4885RECQL 4180/4885ESR2 3995/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.