Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 4/20 | 0.33 |
| ▸ | MMP9 | P14780 | 4/20 | 0.33 |
| ▸ | MMP1 | P03956 | 3/20 | 0.33 |
| ▸ | MMP8 | P22894 | 3/20 | 0.33 |
| ▸ | MMP14 | P50281 | 2/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | EYA2 | O00167 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 3/20 | 0.31 |
| ▸ | MMP3 | P08254 | 2/20 | 0.31 |
| ▸ | MMP16 | P51512 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4962362 | 1.00 | MMP2 (0.33) | MMP2MMP9MMP1MMP8MMP14 | |
| SCHEMBL867976 | 0.81 | TDP1 (0.41) | CYP1A2EYA2APPACETDP1 | |
| SCHEMBL23222802 | 0.80 | ADAMTS4 (0.34) | MMP2MMP9MMP1MMP8MMP14 | |
| Hydrochloric Acid SCHEMBL5577032 | 0.79 | TDP1 (0.39) | CYP1A2EYA2APPACETDP1 | |
| SCHEMBL562830 | 0.72 | FFAR3 (0.38) | CYP1A2EYA2APPACETDP1 | |
| SCHEMBL14502984 | 0.70 | GABRR1 (0.36) | MMP2MMP9MMP1MMP8ADAMTS4 | |
| SCHEMBL28253560 | 0.69 | GABRP (0.33) | — | |
| SCHEMBL28117498 | 0.69 | GABRP (0.33) | — | |
| SCHEMBL3791234 | 0.69 | TP53 (0.38) | MMP2MMP9MMP8MMP14ADAMTS4 | |
| SCHEMBL186528 | 0.69 | TDP1 (0.39) | CYP1A2EYA2APPACETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2453927-B1 | LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE AND IONOPHORE CONTAINING LIPOSOMES IN WHICH THE IONOPHORE IS 2-HYDROXYQUIONOLINE (CARBOSTYRIL) OR STRUCTURALLY RELATED 2-HYDROXYQUINOLINES | UNIV DENMARK TECH DTU (DK) | 2019-05-15 | — | — | EP | disclosed |
| US-20150202336-A1 | Loading Technique for Preparing Radionuclide Containing Nanoparticles | RIGSHOSPITALET (DK) | 2015-07-23 | — | — | US | disclosed |
| US-8920775-B2 | Loading technique for preparing radionuclide containing nanoparticles | TECHNICAL UNIVERSITY OF DENMARK (DK) | 2014-12-30 | — | — | US | disclosed |
| US-20130204121-A1 | NANOPARTICLE-GUIDED RADIOTHERAPY | TECHNICAL UNIVERSITY OF DENMARK (DK) | 2013-08-08 | — | — | US | disclosed |
| EP-2593186-A1 | NANOPARTICLE-GUIDED RADIOTHERAPY | Technical University of Denmark (DK) | 2013-05-22 | — | — | EP | disclosed |
| US-20120213698-A1 | LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE CONTAINING NANOPARTICLES | RIGSHOSPITALET (DK) | 2012-08-23 | — | — | US | disclosed |
| EP-2453927-A1 | LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE AND IONOPHORE CONTAINING LIPOSOMES IN WHICH THE IONOPHORE IS 2-HYDROXYQUIONOLINE (CARBOSTYRIL) OR STRUCTURALLY RELATED 2-HYDROXYQUINOLINES | Technical University of Denmark (DK) | 2012-05-23 | — | — | EP | disclosed |
| WO-2012007567-A1 | NANOPARTICLE-GUIDED RADIOTHERAPY | TECHNICAL UNIVERSITY OF DENMARK (DK) | 2012-01-19 | — | — | WO | disclosed |
| WO-2011006510-A1 | LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE AND IONOPHORE CONTAINING LIPOSOMES IN WHICH THE IONOPHORE IS 2-HYDROXYQUIONOLINE (CARBOSTYRIL) OR STRUCTURALLY RELATED 2-HYDROXYQUINOLINES | TECHNICAL UNIVERSITY OF DENMARK (DK) | 2011-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150202336-A1 | Loading Technique for Preparing Radionuclide Containing Nanoparticles | LIPG, NPC1L1, CD47 | MMP2 2927/4885MMP9 1216/4885MMP1 834/4885 |
| US-20120213698-A1 | LOADING TECHNIQUE FOR PREPARING RADIONUCLIDE CONTAINING NANOPARTICLES | LIPG, NPC1L1, CD47 | MMP2 2927/4885MMP9 1216/4885MMP1 834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.