Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.49 |
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27800319 | 0.89 | CXCL8 (0.53) | CXCL8MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL16539266 | 0.86 | CXCL8 (0.64) | CXCL8MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL14280730 | 0.84 | CXCL8 (0.63) | CXCL8MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4944935 | 0.80 | CXCL8 (0.58) | CXCL8MAPTKMT2AALDH1A1LMNA | |
| SCHEMBL30285203 | 0.79 | ALDH1A1 (0.53) | CXCL8MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL3137707 | 0.79 | CXCL8 (1.00) | CXCL8MAPTMEN1KMT2ALMNA | |
| SCHEMBL3151521 | 0.79 | CXCL8 (1.00) | CXCL8MAPTMEN1KMT2ALMNA | |
| SCHEMBL12129515 | 0.79 | CXCL8 (1.00) | CXCL8MAPTMEN1KMT2ALMNA | |
| SCHEMBL7979001 | 0.79 | TDP1 (0.50) | MAPTMEN1KMT2AALDH1A1ALOX15 | |
| SCHEMBL187738 | 0.79 | CXCL8 (0.56) | CXCL8MAPTALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012008916-A1 | FLAME RETARDANT AND INTUMESCENT COMPOUND | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2012-01-19 | — | — | WO | disclosed |
| US-7034187-B2 | Poly(aralkyl ketone)s and methods of preparing the same | AGENCY FOR SCIENCE, TECHNOLOGY, AND RESEARCH (SG) | 2006-04-25 | — | — | US | disclosed |
| US-20050272905-A1 | NOVEL POLY(ARALKYL KETONE)S AND METHODS OF PREPARING THE SAME | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH | 2005-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050272905-A1 | NOVEL POLY(ARALKYL KETONE)S AND METHODS OF PREPARING THE SAME | ADSL, KHK, PKLR | CXCL8 3796/4885MAPT 3173/4885MEN1 2585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.